Evidence map›Paper›PMID 12067936›Full record

ArticleHeart (British Cardiac Society)2002

Low prevalence of lipid lowering drug use in older men with established coronary heart disease.

P H Whincup, J R Emberson, L Lennon, M Walker, O Papacosta, A Thomson

Open access · bronzeAbstract read
In one paragraph

Article in Heart (British Cardiac Society), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 76 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Missed opportunities in prevention of cardiovascular disease in primary care: a cross-sectional study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
    Article
  5. Statins in the primary prevention of cardiovascular disease.Nature reviews. Cardiology · 2013 · on this map
    Review
  6. Article
  7. Review
  8. Computerized history-taking as a tool to manage dyslipidemia.Vascular health and risk management · 2010
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The use of cholesterol-lowering medications after coronary revascularization.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2003
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

P H WhincupDepartment of Public Health Sciences, St George's Hospital Medical School, London SW17 ORE, UK. p.whincup@sghms.ac.uk
J R Emberson
L Lennon
M Walker
O Papacosta
A Thomson
Roland Hill (United Kingdom) · GBThe Royal Free Hospital · GBSt George's, University of London · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the prevalence and correlates of lipid lowering drug use among older British men with established coronary heart disease (CHD).

designCross sectional survey within a cohort study (British regional heart study) carried out at 20 years of follow up in 1998-2000.

settingGeneral practices in 24 British towns.

participants3689 men aged 60-75 years (response rate 76%).

main outcome measuresDiagnoses of myocardial infarction and angina based on detailed review of general practice records. Lipid lowering drug use and blood cholesterol concentrations ascertained at 20 year follow up examination.

resultsAmong 286 men with definite myocardial infarction, 102 (36%) were taking a lipid lowering drug (93 (33%) a statin); among 360 men with definite angina without myocardial infarction, 84 (23%) were taking a lipid lowering drug (78 (21%) a statin). Most men with documented CHD who were not receiving a lipid lowering drug had a total cholesterol concentration of 5.0 mmol/l or more (87% of those with myocardial infarction, 82% with angina). Fewer than half of men with CHD receiving a statin had a total cholesterol concentration below 5.0 mmol/l (45% of those with myocardial infarction and 47% of those with angina). Only one third of the men taking a statin were receiving trial validated dosages. Among men with CHD, a history of revascularisation, more recent diagnosis, and younger age at diagnosis were associated with a higher probability of receiving lipid lowering drug treatment.

conclusionAmong patients with established CHD, the prevalence of lipid lowering drug use remains low and statin regimens suboptimal. Major improvements in secondary prevention are essential if the benefits of statins are to be realised.

Indexed as

AgedAngina PectorisCholesterolCohort StudiesCross-Sectional StudiesFollow-Up StudiesHumansHypolipidemic AgentsMaleMiddle AgedMyocardial InfarctionPrevalenceProspective StudiesUnited KingdomCholesterolHypolipidemic Agents

Identifiers

PMID12067936
PMCPMC1767195
OpenAlexW2019947564

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.