Evidence map›Paper›PMID 12067933›Full record

ArticleHeart (British Cardiac Society)2002

Use of statins in the secondary prevention of coronary heart disease: is treatment equitable?

F D A Reid, D G Cook, P H Whincup

Abstract read
In one paragraph

Article in Heart (British Cardiac Society), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Cardiovascular risk reduction following diagnosis of diabetes by screening: 1-year results from the ADDITION-Cambridge trial cohort.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012
    Trial
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  3. Multiple Socioeconomic Circumstances and Initiation of Cardiovascular Medication among Ageing Employees.International journal of environmental research and public health · 2021
    Article
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  6. Statin-prescribing trends for primary and secondary prevention of cardiovascular disease.Canadian family physician Medecin de famille canadien · 2017
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

F D A ReidDepartment of Public Health Sciences, St George's Hospital Medical School, London SW17, UK. freid@sghms.ac.uk
D G Cook
P H Whincup

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate possible inequities in the use of statins for people with coronary heart disease according to a wide range of social and clinical factors. DESIGN AND

settingCross sectional analysis of data from the Health Survey for England 1998, a population based survey. SUBJECTS: 760 adults with coronary heart disease.

resultsOnly 19.9% of subjects with coronary heart disease were receiving lipid lowering drugs (151 of 760; 95% confidence interval (CI) 17.0% to 22.7%). The likelihood of receiving statins was greatly reduced for older age groups: compared with those aged less than 65 years, the odds of receiving statin treatment were 0.53 (95% CI 0.35 to 0.80) for subjects aged 65-74 years, and 0.11 (95% CI 0.06 to 0.21) for subjects aged 75 years and over. Statins were given less often to current cigarette smokers than to non-smokers (odds ratio 0.55, 95% CI 0.32 to 0.96), and to subjects with angina compared with those with a previous myocardial infarct (odds ratio 0.63, 95% CI 0.43 to 0.93). Lower levels of statin use were also seen with increasing time since diagnosis (p = 0.12). No clear associations were observed with social measures.

conclusionsImportant inequalities were found in the use of statins among people with coronary heart disease, which could not be justified by evidence from the large statin trials. Proactive policies are required to ensure that the vast majority of (if not all) patients with coronary heart disease are receiving statins, regardless of age, sex, social class, smoking status, type of coronary heart disease, or time since diagnosis.

Indexed as

AdultAgedAged, 80 and overAge DistributionCholesterolCoronary DiseaseCross-Sectional StudiesDelivery of Health CareEnglandFemaleHealth Services AccessibilityHealth SurveysHumansHypolipidemic AgentsMaleMiddle AgedCholesterolHypolipidemic Agents

Identifiers

PMID12067933
PMCPMC1767198

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.