ReviewJournal of cellular and molecular medicine
Altered mucin expression in the gastrointestinal tract: a review.
Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 87 citations in OpenAlex.
- Molecular studies of phages-Frontiers in microbiology · 2023Article
- Characterizing Phage-Host Interactions in a Simplified Human Intestinal Barrier Model.Microorganisms · 2020Article
- Djulis (Nutrients · 2019Article
- Effects of microbial phytase on mucin synthesis, gastric protein hydrolysis, and degradation of phytate along the gastrointestinal tract of growing pigs.Journal of animal science · 2019Article
- The Role of the Cell Surface Mucin MUC1 as a Barrier to Infection and Regulator of Inflammation.Frontiers in cellular and infection microbiology · 2019Review
- Pathogenesis of Inflammatory Bowel Disease and Recent Advances in Biologic Therapies.Immune network · 2017Review
- MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.Virchows Archiv : an international journal of pathology · 2016Article
- Article
- Preventative Effects of Sodium Alginate on Indomethacin-induced Small-intestinal Injury in Mice.International journal of medical sciences · 2016Article
- Cyst fluid biomarkers for intraductal papillary mucinous neoplasms of the pancreas: a critical review from the international expert meeting on pancreatic branch-duct-intraductal papillary mucinous neoplasms.Journal of the American College of Surgeons · 2015Article
- Mitochondrial dysfunction in inflammatory bowel disease.Frontiers in cell and developmental biology · 2015Review
- [Etiopathogenesis of chronic inflammatory bowel diseases. Role of the immune system].Der Internist · 2014Review
- Increasing the α 2, 6 sialylation of glycoproteins may contribute to metastatic spread and therapeutic resistance in colorectal cancer.Gut and liver · 2013Review
- Epithelial tyrosine phosphatase SHP-2 protects against intestinal inflammation in mice.Molecular and cellular biology · 2013Article
- RNA in situ hybridization in whole mount embryos and cell histology adapted for marine elasmobranchs.Journal of visualized experiments : JoVE · 2013Article
- The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine.Cell death & disease · 2011Article
- Infection with the gastrointestinal nematode Ostertagia ostertagi in cattle affects mucus biosynthesis in the abomasum.Veterinary research · 2011Article
- Markers of bile duct tumors.World journal of gastrointestinal oncology · 2011Article
- Pancreatic cyst fluid and serum mucin levels predict dysplasia in intraductal papillary mucinous neoplasms of the pancreas.Annals of surgical oncology · 2011Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early studies of changes in mucin expression in disorders of the gastrointestinal tract focused on alterations in the carbohydrate chain. This review briefly considers the various mechanisms by which such alterations may come about: (a) normal variation, (b) sialic acid alterations, (c) defective assembly of carbohydrate side-chains, (d) changed expression of core proteins and (e) epithelial metaplasia. The availability of monoclonal antibodies to mucin core proteins adds a new dimension to mucin histochemistry. It is now possible to offer explanations for traditional mucin histochemical findings on the basis of lineage-specific patterns of mucin core protein expression. Changes in core protein expression are described in inflammatory, metaplastic and neoplastic disorders of the gastrointestinal tract. The possibility that mucin change could be important in the aetiology of some diseases such as ulcerative colitis and H. pylori gastritis is considered. It is more probable, however, that changes in mucin expression are secondary to reprogramming of cellular differentiation and altered cell turnover. As such they may serve as markers to explain pathogenesis and provide novel diagnostic and prognostic information.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.