Can intestinal helminth infections (geohelminths) affect the development and expression of asthma and allergic disease?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed.

1. A longitudinal study of allergy and intestinal helminth infections in semi urban and rural areas of Flores, Indonesia (ImmunoSPIN Study).BMC infectious diseases · 2011
   Trial
2. Levels of Exhaled Fraction of Nitric Oxide (FeNO) and Type 2 Biomarkers in Individuals Naturally Exposed to Helminth Parasites in a Tropical Region.International journal of molecular sciences · 2025
   Article
3. Expression profiling of ileal mucosa in asthma reveals upregulation of innate immunity and genes characteristic of Paneth and goblet cells.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
   Article
4. Helminth infection induces non-functional sensitization to house dust mites.PloS one · 2021
   Observational
5. Aluminum Adjuvant-Containing Vaccines in the Context of the Hygiene Hypothesis: A Risk Factor for Eosinophilia and Allergy in a Genetically Susceptible Subpopulation?International journal of environmental research and public health · 2018
   Review
6. Cohort Profile: The Ecuador Life (ECUAVIDA) study in Esmeraldas Province, Ecuador.International journal of epidemiology · 2015
   Article
7. Atopy is a risk factor for adult asthma in urban community of Southwestern Nigeria.Lung India : official organ of Indian Chest Society · 2012
   Article
8. Atopy is inversely related to schistosome infection intensity: a comparative study in Zimbabwean villages with distinct levels of Schistosoma haematobium infection.International archives of allergy and immunology · 2012
   Article
9. Infections, medication use, and the prevalence of symptoms of asthma, rhinitis, and eczema in childhood.Journal of epidemiology and community health · 2004
   Article
10. The potential impact of early exposures to geohelminth infections on the development of atopy.Clinical reviews in allergy & immunology · 2004
    Review
11. Parasites and the hygiene hypothesis: regulating the immune system?Clinical reviews in allergy & immunology · 2004
    Review
12. Regulation of allergy and autoimmunity in helminth infection.Clinical reviews in allergy & immunology · 2004
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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