ArticleThe EMBO journal2002
Crystal structure of auxin-binding protein 1 in complex with auxin.
Article in The EMBO journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
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Who cites it
64 citing papers in PubMed, 167 citations in OpenAlex.
- RLCKs phosphorylate RopGEFs to control auxin-dependent Arabidopsis development.Nature plants · 2025Article
- Historical and mechanistic perspective on ABP1-TMK1-mediated cell surface auxin signaling.NPJ science of plants · 2025Review
- The new horizon of plant auxin signaling via cell-surface co-receptors.Cell research · 2024Article
- Article
- New Insights into the Enhancement of Adventitious Root Formation Using N,N'-Bis(2,3-methylenedioxyphenyl)urea.Plants (Basel, Switzerland) · 2023Article
- Canonical and Alternative Auxin Signaling Systems in Mono-, Di-, and Tetraploid Potatoes.International journal of molecular sciences · 2023Article
- Article
- The Story of Auxin-Binding Protein 1 (ABP1).Cold Spring Harbor perspectives in biology · 2021Review
- Ligand-Binding-Site Structure Refinement Using Molecular Dynamics with Restraints Derived from Predicted Binding Site Templates.Journal of chemical theory and computation · 2019Article
- Chilli leaf curl virus infection downregulates the expression of the genes encoding chloroplast proteins and stress-related proteins.Physiology and molecular biology of plants : an international journal of functional plant biology · 2019Article
- Auxin Signaling.Plant physiology · 2018Review
- The Effect of Naphthazarin on the Growth, Electrogenicity, Oxidative Stress, and Microtubule Array inFrontiers in plant science · 2018Article
- Molecular machinery of auxin synthesis, secretion, and perception in the unicellular chlorophyte alga Chlorella sorokiniana UTEX 1230.PloS one · 2018Article
- Protoplast Swelling and Hypocotyl Growth Depend on Different Auxin Signaling Pathways.Plant physiology · 2017Article
- A novel function for globulin in sequestering plant hormone: Crystal structure of Wrightia tinctoria 11S globulin in complex with auxin.Scientific reports · 2017Article
- An Effective Strategy for Reliably Isolating Heritable and Cas9-Free Arabidopsis Mutants Generated by CRISPR/Cas9-Mediated Genome Editing.Plant physiology · 2016Article
- Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily.PloS one · 2016Article
- Strong morphological defects in conditional Arabidopsis abp1 knock-down mutants generated in absence of functional ABP1 protein.F1000Research · 2016Article
- Interactions of Indole Derivatives with β-Cyclodextrin: A Quantitative Structure-Property Relationship Study.PloS one · 2016Article
- Revisiting Apoplastic Auxin Signaling Mediated by AUXIN BINDING PROTEIN 1.Molecules and cells · 2015Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The structure of auxin-binding protein 1 (ABP1) from maize has been determined at 1.9 A resolution, revealing its auxin-binding site. The structure confirms that ABP1 belongs to the ancient and functionally diverse germin/seed storage 7S protein superfamily. The binding pocket of ABP1 is predominantly hydrophobic with a metal ion deep inside the pocket coordinated by three histidines and a glutamate. Auxin binds within this pocket, with its carboxylate binding the zinc and its aromatic ring binding hydrophobic residues including Trp151. There is a single disulfide between Cys2 and Cys155. No conformational rearrangement of ABP1 was observed when auxin bound to the protein in the crystal, but examination of the structure reveals a possible mechanism of signal transduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.