ArticleProceedings of the National Academy of Sciences of the United States of America2002
Comparative genomic analysis in the region of a major Plasmodium-refractoriness locus of Anopheles gambiae.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Epigenetic Regulation of Endothelial Cell Lineages During Zebrafish Development-New Insights From Technical Advances.Frontiers in cell and developmental biology · 2022Review
- SNP discovery and molecular evolution in Anopheles gambiae, with special emphasis on innate immune system.BMC genomics · 2008Article
- Article
- Update of the Anopheles gambiae PEST genome assembly.Genome biology · 2007Article
- Article
- Genomic analysis of a 1 Mb region near the telomere of Hessian fly chromosome X2 and avirulence gene vH13.BMC genomics · 2006Article
- Comparison of the oxidative phosphorylation (OXPHOS) nuclear genes in the genomes of Drosophila melanogaster, Drosophila pseudoobscura and Anopheles gambiae.Genome biology · 2005Article
- Genomic analysis in the sting-2 quantitative trait locus for defensive behavior in the honey bee, Apis mellifera.Genome research · 2003Article
- Quantitative trait loci in Anopheles gambiae controlling the encapsulation response against Plasmodium cynomolgi Ceylon.BMC genetics · 2003Article
- Construction of a BAC library and generation of BAC end sequence-tagged connectors for genome sequencing of the African malaria mosquito Anopheles gambiae.Molecular genetics and genomics : MGG · 2003Article
- Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome.Genome biology · 2002Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
We have sequenced six overlapping clones from a library of bacterial artificial chromosome (BAC) clones derived from a laboratory strain of the mosquito, Anopheles gambiae, the major vector of human malaria in Africa. The resulting uninterrupted 528-kb sequence is from the 8C region of the mosquito 2R chromosome, at or very near the major refractoriness locus associated with melanotic encapsulation of parasites. This sequence represents the first extensive view of the mosquito genome structure encompassing 48 genes. Genomic comparison reveals that the majority of the orthologues are found in six microsyntenic clusters in Drosophila melanogaster. A BAC clone that is wholly contained within this region demonstrates the existence of a remarkable degree of local polymorphism in this species, which may prove important for its population structure and vectorial capacity.
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