ArticleMolecular biology of the cell2002
The G1/S cyclin Cig2p during meiosis in fission yeast.
Article in Molecular biology of the cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 38 citations in OpenAlex.
- CDK phosphorylation of Sfr1 downregulates Rad51 function in late-meiotic homolog invasions.The EMBO journal · 2024Article
- The Meiosis-Specific Crs1 Cyclin Is Required for Efficient S-Phase Progression and Stable Nuclear Architecture.International journal of molecular sciences · 2021Article
- Phospho-Regulation of Meiotic Prophase.Frontiers in cell and developmental biology · 2021Review
- Modeling the Control of Meiotic Cell Divisions: Entry, Progression, and Exit.Biophysical journal · 2020Article
- CDK Regulation of Meiosis: Lessons fromGenes · 2020Review
- CDK contribution to DSB formation and recombination in fission yeast meiosis.PLoS genetics · 2019Article
- Genome-wide screen for cell growth regulators in fission yeast.Journal of cell science · 2017Article
- Review
- Cdk3, a conjugation-specific cyclin-dependent kinase, is essential for the initiation of meiosis in Tetrahymena thermophila.Cell cycle (Georgetown, Tex.) · 2016Article
- A single cyclin-CDK complex is sufficient for both mitotic and meiotic progression in fission yeast.Nature communications · 2015Article
- Recent advances in understanding of meiosis initiation and the apomictic pathway in plants.Frontiers in plant science · 2014Review
- Regulation of wee1(+) expression during meiosis in fission yeast.Cell cycle (Georgetown, Tex.) · 2014Article
- Control of the meiotic cell division program in plants.Plant reproduction · 2013Review
- Anaphase-promoting complex/cyclosome-mediated proteolysis of Ams2 in the G1 phase ensures the coupling of histone gene expression to DNA replication in fission yeast.The Journal of biological chemistry · 2013Article
- The selective elimination of messenger RNA underlies the mitosis-meiosis switch in fission yeast.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2010Review
- Cohesin and recombination proteins influence the G1-to-S transition in azygotic meiosis in Schizosaccharomyces pombe.Genetics · 2008Article
- Regulating the formation of DNA double-strand breaks in meiosis.Genes & development · 2008Article
- Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis.Genome dynamics and stability · 2008Article
- Mei4p coordinates the onset of meiosis I by regulating cdc25+ in fission yeast.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Molecular mechanisms underlying the mitosis-meiosis decision.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2007Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyclin-dependent kinases (CDKs) are important for both mitotic and meiotic cell cycles. In fission yeast, the major CDK, Cdc2p is involved in premeiotic DNA replication and in meiosis II. One of its partners, the mitotic cyclin Cdc13p is known to be required for meiosis, whereas there are no studies on the G1/S cyclin Cig2p. In this article, we have studied the regulation of the Cdc2p/Cdc13p and Cdc2p/Cig2p complexes during synchronous meiosis. We observed that Cdc2p/Cig2p kinase is activated in an unexpected biphasic manner, first at onset of premeiotic S phase and again during meiotic nuclear divisions. The role of Cig2p during meiosis was investigated using cig2-deleted strains that exhibit delays in onset of both S phase and meiotic divisions as well as an inefficient completion of MII. Furthermore, analysis of cig2 transcripts revealed a meiosis-specific regulation of cig2 expression during MI/MII dependent upon the Mei4p transcription factor leading to a different transcription start site at this stage of meiosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.