ArticleBMJ (Clinical research ed.)2002
Detecting patients at a high risk of developing chronic obstructive pulmonary disease in general practice: cross sectional case finding study.
Article in BMJ (Clinical research ed.), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01880177 (A Study Designed to Develop and Validate a New Screening Measure for Identifying Undiagnosed At-Risk COPD Cases), which is not on this map. Cited by 71 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Study Designed to Develop and Validate a New Screening Measure for Identifying Undiagnosed At-Risk COPD Cases
Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 275 citations in OpenAlex.
- Effectiveness of case finding strategies for COPD in primary care: a systematic review and meta-analysis.NPJ primary care respiratory medicine · 2015Pooled it
- Guidelines for the management of adult lower respiratory tract infections--full version.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2011Guideline
- TargetCOPD: a pragmatic randomised controlled trial of targeted case finding for COPD versus routine practice in primary care: protocol.BMC pulmonary medicine · 2014Trial
- Effectiveness of spirometry as a motivational tool for smoking cessation: a clinical trial, the ESPIMOAT study.BMC family practice · 2013Trial
- Early detection of COPD in general practice: patient or practice managed? A randomised controlled trial of two strategies in different socioeconomic environments.Primary care respiratory journal : journal of the General Practice Airways Group · 2013Trial
- Effectiveness of regular reporting of spirometric results combined with a smoking cessation advice by a primary care physician on smoking quit rate in adult smokers: a randomized controlled trial. ESPIROTAB study.BMC family practice · 2011Trial
- Effect on smoking quit rate of telling patients their lung age: the Step2quit randomised controlled trial.BMJ (Clinical research ed.) · 2008Trial
- Improving Care for People with Chronic Respiratory Diseases: Taking a Policy Lens.Advances in therapy · 2025Review
- Review
- Identifying Existing Evidence to Potentially Develop a Machine Learning Diagnostic Algorithm for Cough in Primary Care Settings: Scoping Review.Journal of medical Internet research · 2023Article
- Cough in chronic lung disease: a state of the art review.Journal of thoracic disease · 2023Review
- Smoking cessation policy and treatments derived from the protective motivation of smokers: a study on graphic health warning labels.Frontiers in psychology · 2023Article
- Challenges to Implementation of Community Health Worker-Led Chronic Obstructive Pulmonary Disease (COPD) Screening and Referral in Rural Uganda: A Qualitative Study using the Implementation Outcomes Framework.International journal of chronic obstructive pulmonary disease · 2023Article
- Accuracy of the COPD diagnostic questionnaire as a screening tool in primary care.BMC primary care · 2022Article
- The Burden of Cough and Phlegm in People With COPD: A COPD Patient-Powered Research Network Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2020Article
- The feasibility of an innovative GP-physiotherapist partnership to identify and manage chronic obstructive pulmonary disease (INTEGRATED): study protocol.Pilot and feasibility studies · 2020Article
- The effects of psychological distress and its interaction with socioeconomic position on risk of developing four chronic diseases.Journal of psychosomatic research · 2018Article
- Chronic obstructive lung disease "expert system": validation of a predictive tool for assisting diagnosis.International journal of chronic obstructive pulmonary disease · 2018Article
- Effect of telling patients their "spirometric-lung-age" on smoking cessation in Japanese smokers.Journal of thoracic disease · 2017Article
- Voluntary lung function screening to reveal new COPD cases in southern Italy.International journal of chronic obstructive pulmonary disease · 2017Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the effectiveness of case finding of patients at risk of developing chronic obstructive pulmonary disease, whether the method is suitable for use in general practice, how patients should be selected, and the time required.
designCross sectional study.
settingTwo semirural general practices in the Netherlands.
participants651 smokers aged 35 to 70 years.
main outcome measuresShort standardised questionnaire on bronchial symptoms for current smokers, lung function with a spirometer, and the quality of the spirometric curve.
resultsOf the 201 smokers not taking drugs for a pulmonary condition, 169 produced an acceptable curve (fulfilling American Thoracic Society criteria). Of these, 30 (18%, 95% confidence interval 12% to 24%) had a forced expiratory volume in one second (FEV(1)) <80% of predicted. When smokers were preselected on the basis of chronic cough, the proportion with an FEV(1) <80% of predicted increased to 27% (17 of 64; 12% to 38%). Chronic cough was a better predictor of airflow obstruction than other symptoms, such as wheeze and dyspnoea. The presence of two symptoms was a slightly better predictor than cough only (odds ratio 3.02 (1.37 to 6.64) v 2.50 (1.14 to 5.52)). Age was also a good predictor of obstruction; smokers over 60 with cough had a 48% chance of having an obstruction. The mean time needed for spirometry was four minutes. Detecting one smoker with an FEV(1) <80% of predicted cost 5 pound sterling to 10 pound sterling.
conclusionsTrained practice assistants could check all patients who smoke for chronic obstructive pulmonary disease at little cost to the practice. Cough and age are the most important predictors of the disease. By testing one smoker a day, an average practice could identify one patient at risk a week.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.