ArticleThe Biochemical journal2002
Identification and characterization of GSTT3, a third murine Theta class glutathione transferase.
Article in The Biochemical journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Sodium Hydrosulfide Protects Rats from Hypobaric-Hypoxia-Induced Acute Lung Injury.International journal of molecular sciences · 2024Article
- Bisphenol S leads to cytotoxicity-induced antioxidant responses and oxidative stress in isolated rainbow trout (Oncorhyncus mykiss) hepatocytes.Molecular biology reports · 2021Article
- Functional, Structural and Biochemical Features of Plant Serinyl-Glutathione Transferases.Frontiers in plant science · 2019Review
- Effect of nine diets on mRNAs of phase-II conjugation enzymes in livers of mice.Xenobiotica; the fate of foreign compounds in biological systems · 2017Article
- The Genetic Architecture of Murine Glutathione Transferases.PloS one · 2016Article
- In-depth identification of pathways related to cisplatin-induced hepatotoxicity through an integrative method based on an informatics-assisted label-free protein quantitation and microarray gene expression approach.Molecular & cellular proteomics : MCP · 2012Article
- Ncb5or deficiency increases fatty acid catabolism and oxidative stress.The Journal of biological chemistry · 2011Article
- Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology.Human genomics and proteomics : HGP · 2010Article
- Isoenzyme-specific up-regulation of glutathione transferase and aldo-keto reductase mRNA expression by dietary quercetin in rat liver.Molecular and cellular biochemistry · 2009Article
- Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase.The Biochemical journal · 2003Article
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Authors and funding
6 authors.
Funding
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Abstract
A novel Theta class glutathione transferase (GST) isoenzyme from mouse termed mGSTT3 has been identified by analysis of the expressed sequence tag database. The gene encoding mGSTT3 is clustered with the mGSTT1 and mGSTT2 genes on chromosome 10 and has an exon/intron structure that is similar to that of the other Theta class genes. mGSTT3 is expressed strongly in the liver and to a decreasing extent in the kidney and testis. Recombinant mGSTT3-3 expressed in Escherichia coli had a substrate-specificity profile that differed significantly from that of GSTT1-1 and GSTT2-2 isoenzymes. A molecular model of mGSTT3 suggested that, in comparison with GSTT2, a decrease in volume of the hydrophobic substrate-binding site and the loss of the sulphate-binding pocket prevents its use of the GSTT2 substrate 1-menaphthyl sulphate.
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