ArticleJournal of clinical microbiology2002
Genotyping study of Scedosporium apiospermum isolates from patients with cystic fibrosis.
Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- Fungal Colonization of the Airways of Patients with Cystic Fibrosis: the Role of the Environmental Reservoirs.Mycopathologia · 2024Review
- In host evolution of Exophiala dermatitidis in cystic fibrosis lung micro-environment.G3 (Bethesda, Md.) · 2023Article
- What is the best technic to dislodge Staphylococcus epidermidis biofilm on medical implants?BMC microbiology · 2022Article
- The Glycosylphosphatidylinositol-Anchored Superoxide Dismutase ofJournal of fungi (Basel, Switzerland) · 2021Article
- Multilocus Sequence Typing Reveals Extensive Genetic Diversity of the Emerging Fungal PathogenFrontiers in cellular and infection microbiology · 2021Article
- Comparative transcriptome analysis unveils the adaptative mechanisms ofComputational and structural biotechnology journal · 2020Article
- Enzymatic Mechanisms Involved in Evasion of Fungi to the Oxidative Stress: Focus on Scedosporium apiospermum.Mycopathologia · 2018Review
- Challenges in Laboratory Detection of Fungal Pathogens in the Airways of Cystic Fibrosis Patients.Mycopathologia · 2018Article
- Ecology of Scedosporium Species: Present Knowledge and Future Research.Mycopathologia · 2018Review
- Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?Clinical microbiology reviews · 2017Review
- Pathogenesis of Fungal Infections in Cystic Fibrosis.Current fungal infection reports · 2016Review
- Antibiotic management of lung infections in cystic fibrosis. II. Nontuberculous mycobacteria, anaerobic bacteria, and fungi.Annals of the American Thoracic Society · 2014Review
- Validation of a novel real-time PCR for detecting Rasamsonia argillacea species complex in respiratory secretions from cystic fibrosis patients.New microbes and new infections · 2014Article
- Impact of multidrug-resistant organisms on patients considered for lung transplantation.Infectious disease clinics of North America · 2013Review
- Achromobacter xylosoxidans respiratory tract infection in cystic fibrosis patients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2011Article
- Development and validation of a multiplex PCR for detection of Scedosporium spp. in respiratory tract specimens from patients with cystic fibrosis.Journal of clinical microbiology · 2011Article
- Identification of Pseudallescheria and Scedosporium species by three molecular methods.Journal of clinical microbiology · 2011Article
- Clinical significance of microbial infection and adaptation in cystic fibrosis.Clinical microbiology reviews · 2011Review
- Disseminated Scedosporium/Pseudallescheria infection after double-lung transplantation in patients with cystic fibrosis.Journal of clinical microbiology · 2010Article
- The changing microbial epidemiology in cystic fibrosis.Clinical microbiology reviews · 2010Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Usually a saprophyte, Scedosporium apiospermum often colonizes the respiratory tracts of patients with cystic fibrosis (CF). In order to improve our understanding of the molecular epidemiology of the airway colonization, 129 sequential and multiple isolates collected from January 1998 to March 1999 from nine CF patients monitored in three hospitals in France were typed by random amplification of polymorphic DNA with primers GC70, UBC-701, and UBC-703. Among these primers, UBC-703 was the most discriminating, allowing the differentiation of 14 genotypes. Combining the results obtained with this three-primer set resulted in the differentiation of 16 genotypes. No common genotype was found among the different patients, and no clustering according to geographic origin of the isolates was seen. In addition, five of the patients were colonized by a single genotype. The others usually exhibited a predominant genotype accompanied by one or two others, which were found occasionally and were genetically close to the predominant genotype. Thus, our study demonstrates the persistence of the fungus despite antifungal treatments and therefore reinforces the need for the development of new antifungals that are more efficient against this species.
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