ArticleJournal of clinical microbiology2002
DNA microarray-based typing of an atypical monophasic Salmonella enterica serovar.
Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 97 citations in OpenAlex.
- Epidemiological Surveillance, Variability, and Evolution of Isolates Belonging to the Spanish Clone of the 4,[5],12:i:- Monophasic Variant ofAntibiotics (Basel, Switzerland) · 2025Article
- Genomic characteristics and antibiotic resistance profiles of monophasicFrontiers in microbiology · 2025Article
- Mapping foodborne pathogen contamination throughout the conventional and alternative poultry supply chains.Poultry science · 2021Review
- Sequence Analyses and Phenotypic Characterization Revealed Multidrug Resistant Gene Insertions in the Genomic Region Encompassing Phase 2 Flagellin EncodingFrontiers in microbiology · 2021Article
- Population structure, case clusters, and genetic lesions associated with Canadian Salmonella 4,[5],12:i:- isolates.PloS one · 2021Article
- Genotyping Study ofMicroorganisms · 2020Article
- Article
- Non-typhoidalPathogens (Basel, Switzerland) · 2019Review
- A Comparative Genomic Analysis Provides Novel Insights Into the Ecological Success of the MonophasicFrontiers in microbiology · 2018Article
- Molecular typing of Salmonella enterica serovar 4,[5],12:i:- isolates from humans, animals and river water in Japan by multilocus variable-number tandem repeat analysis and pulsed-field gel electrophoresis.The Journal of veterinary medical science · 2015Article
- Prevalence and Characterization of Monophasic Salmonella Serovar 1,4,[5],12:i:- of Food Origin in China.PloS one · 2015Article
- Characteristics of Salmonella enterica serovar 4,[5],12:i:- as a monophasic variant of serovar Typhimurium.PloS one · 2014Article
- Genetic types, gene repertoire, and evolution of isolates of the Salmonella enterica serovar 4,5,12:i:- Spanish clone assigned to different phage types.Journal of clinical microbiology · 2013Article
- Genetic relationships of phage types and single nucleotide polymorphism typing of Salmonella enterica Serovar Typhimurium.Journal of clinical microbiology · 2012Article
- Molecular determination of H antigens of Salmonella by use of a microsphere-based liquid array.Journal of clinical microbiology · 2011Article
- Genetic evolution of the Spanish multidrug-resistant Salmonella enterica 4,5,12:i:- monophasic variant.Journal of clinical microbiology · 2010Article
- Pork contaminated with Salmonella enterica serovar 4,[5],12:i:-, an emerging health risk for humans.Applied and environmental microbiology · 2010Article
- Comparison of genotypes of Salmonella enterica serovar Enteritidis phage type 30 and 9c strains isolated during three outbreaks associated with raw almonds.Applied and environmental microbiology · 2010Article
- Pulsed-field gel electrophoresis diversity of human and bovine clinical Salmonella isolates.Foodborne pathogens and disease · 2010Article
- Identification by PCR of non-typhoidal Salmonella enterica serovars associated with invasive infections among febrile patients in Mali.PLoS neglected tropical diseases · 2010Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
A multidrug-resistant fljB-lacking Salmonella enterica serovar [4,5,12:i:-] emerged in Spain in 1997. We analyzed the genome from four strains of this serovar using a microarray containing almost all the predicted protein coding regions of serovar Typhimurium strain LT2, including the pSLT plasmid. Only a few differences from serovar Typhimurium LT2 were observed, suggesting the serovar to be Typhimurium as well. Six regions of interest were identified from the microarray data. Cluster I was a deletion of 13 genes, corresponding to part of the regulon responsible for the anaerobic assimilation of allantoin. Clusters II and IV were associated with the absence of the Fels-1 and Fels-2 prophage. Cluster III was a small group of Gifsy-1 prophage-related genes that appeared to be deleted or replaced. Cluster V was a deletion of 16 genes, including iroB and the operon fljAB, which is reflected in the serovar designation. Region VI was the gene STM2240, which appears to have an additional homologue in these strains. The regions spanning the deletions involving the allantoin operon and the fljAB operon were PCR amplified and sequenced. PCR across these regions may be an effective marker for this particular emergent serovar. While the microarray data for all isolates of the new serovar were essentially identical for all LT2 chromosomal genes, the isolates differed in their similarity to pSLT, consistent with the heterogeneity in plasmid content among isolates of the new serovar. Recent isolates have acquired a more-complete subset of homologues to this virulence plasmid. In general, microarrays can provide useful complementary data to other typing methods.
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