Evidence map›Paper›PMID 12036263›Full record

ReviewPlant molecular biology

The role of regulated protein degradation in auxin response.

Sunethra Dharmasiri, Mark Estelle

Abstract readReview
PubMed
In one paragraph

Review in Plant molecular biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
24.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 138 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Genome-Wide Analysis and Characterization of theInternational journal of molecular sciences · 2019
    Article
  5. Article
  6. Article
  7. Article
  8. Role of microRNAs in plant drought tolerance.Plant biotechnology journal · 2015
    Review
  9. Article
  10. Assaying proteasomal degradation in a cell-free system in plants.Journal of visualized experiments : JoVE · 2014
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The ubiquitin-proteasome system regulates plant hormone signaling.The Plant journal : for cell and molecular biology · 2010
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sunethra DharmasiriInstitute for Cellular and Molecular Biology, Section of Molecular Cell and Developmental Biology, University of Texas at Austin, USA.
Mark Estelle
The University of Texas at Austin · US

Funding

PHS HHS 43644
6 · The paper itself

Abstract

Auxin-regulated gene expression is mediated by two families of transcription factors. The ARF proteins bind to a conserved DNA sequence called the AuxRE and activate transcription. The Aux/IAA proteins repress ARF function, presumably by forming dimers with ARF proteins. Recent genetic studies in Arabidopsis indicate that auxin regulates this system by promoting the ubiquitin-mediated degradation of the Aux/IAA proteins, thus permitting ARF function. Mutations in components of SCF(TIR1), a ubiquitin protein ligase (E3) result in stabilization of Aux/IAA proteins and decreased auxin response. Further, recent biochemical experiments indicate that the Aux/IAA proteins bind SCF(TIR1) in an auxin-dependent manner.

Indexed as

ArabidopsisCysteine EndopeptidasesGene Expression Regulation, PlantIndoleacetic AcidsModels, BiologicalMultienzyme ComplexesPlant ProteinsPlantsProteasome Endopeptidase ComplexProtein BindingSignal TransductionTranscription FactorsUbiquitinCysteine EndopeptidasesIndoleacetic AcidsMultienzyme ComplexesPlant ProteinsProteasome Endopeptidase ComplexTranscription FactorsUbiquitin

Identifiers

PMID12036263
OpenAlexW1583276822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.