Evidence map›Paper›PMID 12032650›Full record

Trial reportEuropean journal of clinical nutrition2002

The long-term effect of dietary advice in men with coronary disease: follow-up of the Diet and Reinfarction trial (DART).

A R Ness, J Hughes, P C Elwood, E Whitley, G D Smith, M L Burr

Abstract readClinical TrialRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Dietary advice for people with schizophrenia.The Cochrane database of systematic reviews · 2016
    Pooled it
  9. Omega 3 fatty acids for prevention and treatment of cardiovascular disease.The Cochrane database of systematic reviews · 2004
    Pooled it
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Dietary fibers and cardiometabolic diseases.International journal of molecular sciences · 2012
    Article
  18. Review
  19. Are dietary recommendations for the use of fish oils sustainable?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2009
    Article
  20. Omega 3 : where do we stand?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A R NessDepartment of Social Medicine, University of Bristol, Bristol, UK. Andy.Ness@bris.ac.uk
J Hughes
P C Elwood
E Whitley
G D Smith
M L Burr

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the long-term effect of dietary advice on diet and mortality after a randomised trial of men with a recent history of myocardial infarction.

designQuestionnaire survey and mortality follow-up after a trial of dietary advice.

settingTwenty-one hospitals in south Wales and south-west England. SUBJECTS: Former participants in the Diet and Reinfarction Trial.

main outcome measuresCurrent fish intake and cereal fibre intake. All-cause mortality, stroke mortality and coronary mortality.

resultsBy February 2000, after 21147 person years of follow-up, 1083 (53%) of the men had died. Completed questionnaires were obtained from 879 (85%) of the 1030 men alive at the beginning of 1999. Relative increases in fish and fibre intake were still present at 10 y but were much smaller. The early reduction in all-cause mortality observed in those given fish advice (unadjusted hazard 0.70 (95% CI 0.54, 0.92)) was followed by an increased risk over the next 3 y (unadjusted hazard 1.31 (95% CI 1.01, 1.70). Fat and fibre advice had no clear effect on coronary or all-cause mortality. The risk of stroke death was increased in the fat advice group-the overall unadjusted hazard was 2.03 (95% CI 1.14, 3.63).

conclusionsIn this follow-up of a trial of intensive dietary advice following myocardial infarction we did not observe any substantial long-term survival benefit. Further trials of fish and fibre advice are feasible and necessary to clarify the role of these foods in coronary disease.

Indexed as

SeafoodAnimalsCoronary DiseaseDietary FatsDietary FiberDiet SurveysEdible GrainFishesFollow-Up StudiesHumansMaleMyocardial InfarctionPatient ComplianceRecurrenceRisk FactorsStrokeDietary FatsDietary Fiber

Identifiers

PMID12032650

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.