ArticleProceedings of the National Academy of Sciences of the United States of America2002
A rice spotted leaf gene, Spl7, encodes a heat stress transcription factor protein.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.
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129 citing papers in PubMed, 358 citations in OpenAlex.
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- Heat stress impact on rice reproductive processes: challenges and new approaches.Frontiers in genome editing · 2026Review
- Functional Characterization of Rice Spotted-Leaf MutantPlants (Basel, Switzerland) · 2025Article
- Rational design of promoter editing confers multipathogen resistance in rice.Genome biology · 2025Article
- The Histidine-25-Arginine Mutation in the Rice MACPF Protein OsCAD1 Induces Cell Death and Activates Defense Responses in the Lesion Mimic Mutant spl17.Rice (New York, N.Y.) · 2025Article
- OsCDPK24 and OsCDPK28 phosphorylate heat shock factor OsHSFA4d to orchestrate abiotic and biotic stress responses in rice.Nature communications · 2025Article
- Lesion Mimic Mutant: An Ideal Genetic Material for Deciphering the Balance Between Plant Immunity and Growth.Rice (New York, N.Y.) · 2025Review
- Phytoalexin deficient 4 is associated with the lesion mimic trait in watermelon clalm mutant (Citrullus lanatus).BMC plant biology · 2025Article
- Adverse effects of heat shock in rice (Heliyon · 2024Review
- A Novel Single Base Mutation inInternational journal of molecular sciences · 2024Article
- Genome-Wide Identification and Expression Analysis of theCurrent issues in molecular biology · 2024Article
- SPL50 Regulates Cell Death and Resistance to Magnaporthe Oryzae in Rice.Rice (New York, N.Y.) · 2024Article
- Integrating physiological and multi-omics methods to elucidate heat stress tolerance for sustainable rice production.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
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- PbHsfC1a-coordinates ABA biosynthesis and HPlant biotechnology journal · 2024Article
- Genetic characterization and linkage analysis of spotted leaf 6,liguleless and lax panicle traits in mutant rice.Journal of genetics · 2024Article
69 more citing papers are in PubMed but not listed here.
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5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A rice spotted leaf (lesion-mimic) gene, Spl7, was identified by map-based cloning. High-resolution mapping with cleaved amplified polymorphic sequence markers enabled us to define a genomic region of 3 kb as a candidate for Spl7. We found one ORF that showed high similarity to a heat stress transcription factor (HSF). Transgenic analysis verified the function of the candidate gene for Spl7: leaf spot development was suppressed in spl7 mutants with a wild-type Spl7 transgene. Thus, we conclude that Spl7 encodes the HSF protein. The transcript of spl7 was observed in mutant plants. The levels of mRNAs (Spl7 in wild type and spl7 in mutant) increased under heat stress. Sequence analysis revealed only one base substitution in the HSF DNA-binding domain of the mutant allele, causing a change from tryptophan to cysteine.
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