ArticleBiophysical journal2002
Membrane tethers formed from blood cells with available area and determination of their adhesion energy.
Article in Biophysical journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 74 citations in OpenAlex.
- Morphological Characteristics, Hemoglobin Content, and Membrane Mechanical Properties of Red Blood Cell Delivery Systems.ACS applied materials & interfaces · 2022Article
- Red Blood Cells: Tethering, Vesiculation, and Disease in Micro-Vascular Flow.Diagnostics (Basel, Switzerland) · 2021Article
- Nucleic Acid Delivery with Red-Blood-Cell-Based Carriers.International journal of molecular sciences · 2021Review
- Cytoskeletal-based mechanisms differently regulateHaematologica · 2021Article
- Prospects for Human Erythrocyte Skeleton-Bilayer Dissociation during Splenic Flow.Biophysical journal · 2017Article
- Mechanics of tissue compaction.Seminars in cell & developmental biology · 2015Review
- Quantifying Molecular-Level Cell Adhesion on Electroactive Conducting Polymers using Electrochemical-Single Cell Force Spectroscopy.Scientific reports · 2015Article
- Phosphatidylinositol 4,5-bisphosphate alters the number of attachment sites between ezrin and actin filaments: a colloidal probe study.The Journal of biological chemistry · 2014Article
- Lipid bilayer and cytoskeletal interactions in a red blood cell.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Development of membrane mechanical function during terminal stages of primitive erythropoiesis in mice.Experimental hematology · 2013Article
- Unexpected membrane dynamics unveiled by membrane nanotube extrusion.Biophysical journal · 2013Article
- Tangential tether extraction and spontaneous tether retraction of human neutrophils.Biophysical journal · 2012Article
- How cholesterol regulates endothelial biomechanics.Frontiers in physiology · 2012Article
- Effects of cholesterol on nano-mechanical properties of the living cell plasma membrane.Soft matter · 2012Article
- The viscoelastic properties of microvilli are dependent upon the cell-surface molecule.Biochemical and biophysical research communications · 2010Article
- Multiscale simulation of erythrocyte membranes.Physical review. E, Statistical, nonlinear, and soft matter physics · 2010Article
- Computational analysis of the tether-pulling experiment to probe plasma membrane-cytoskeleton interaction in cells.Physical review. E, Statistical, nonlinear, and soft matter physics · 2009Article
- Role of E-cadherin in membrane-cortex interaction probed by nanotube extrusion.Biophysical journal · 2009Article
- Human neutrophil surface protrusion under a point load: location independence and viscoelasticity.American journal of physiology. Cell physiology · 2008Article
- Effect of the haematocrit layer geometry on Plasmodium falciparum static thin-layer in vitro cultures.Malaria journal · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Fundamental to all mammalian cells is the adherence of the lipid bilayer membrane to the underlying membrane associated cytoskeleton. To investigate this adhesion, we physically detach the lipid membrane from the cell by mechanically forming membrane tethers. For the most part these have been tethers formed from either neutrophils or red cells. Here we do a simple thermodynamic analysis of the tether formation process using the entire cell, including tether, as the control volume. For a neutrophil, we show that the total adhesion energy per unit area between lipid membrane and cytoskeleton depends on the square of the tether force. For a flaccid red cell, we show that the total adhesion energy minus the tension in the spectrin cytoskeleton depends also on the square of the tether force. Finally, we discuss briefly the viscous flow of membrane. Using published data we calculate and compare values for the various adhesion energies and viscosities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.