Evidence map›Paper›PMID 12021369›Full record

ArticleJournal of virology2002

Minute virus of mice small nonstructural protein NS2 interacts and colocalizes with the Smn protein.

Philip J Young, Klaus T Jensen, Lisa R Burger, David J Pintel, Christian L Lorson

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Distinct evolutionary patterns of endemic and emerging parvoviruses and the origin of a new pandemic virus.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Philip J YoungDepartment of Biology, Arizona State University, Tempe, Arizona 85287, USA.
Klaus T Jensen
Lisa R Burger
David J Pintel
Christian L Lorson
University of Missouri · USArizona State University · US

Funding

Parvovirus RNA Processing and Gene Expression StrategiesR01AI046458 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI PINTEL, DAVID J. · 2000 to 2018
$4.6M
Determinants that regulate splicing of SMNR01NS041584 · NINDS · UNIVERSITY OF MISSOURI-COLUMBIA · PI LORSON, CHRISTIAN L. · 2001 to 2010
$2.8M
MOLECULAR &GENETIC ANALYSIS OF MVM GENE EXPRESSIONR01AI021302 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI PINTEL, DAVID J. · 1985 to 2008
$2.4M
NIAID NIH HHS R01 AI021302NIAID NIH HHS R01 AI046458NIAID NIH HHS R01 AI21302NIAID NIH HHS R01 AI46458NINDS NIH HHS R01 NS041584NINDS NIH HHS R01 NS41584-01
6 · The paper itself

Abstract

The small nonstructural protein NS2 of the minute virus of mice (MVM) is required for efficient viral replication, although its mode of action is unclear. Here we demonstrate that NS2 and survival motor neuron protein (Smn) interact in vitro and in vivo. NS2 and Smn also colocalize in infected nuclei at late times following MVM infection.

Indexed as

AnimalsCell LineCell NucleusCyclic AMP Response Element-Binding ProteinHumansMiceMinute Virus of MiceNerve Tissue ProteinsParvoviridae InfectionsRNA-Binding ProteinsSMN Complex ProteinsViral Nonstructural ProteinsVirus ReplicationCyclic AMP Response Element-Binding ProteinNerve Tissue ProteinsRNA-Binding ProteinsSMN Complex ProteinsViral Nonstructural Proteins

Identifiers

PMID12021369
PMCPMC136193
OpenAlexW2156363086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.