ArticleThe Journal of cell biology2002
Identification of a novel population of muscle stem cells in mice: potential for muscle regeneration.
Article in The Journal of cell biology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03633565 (A Comparative Study of Strategies for Management of Duchenne Myopathy in Assiut University Children Hospital), which is not on this map. Cited by 289 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Comparative Study of Strategies for Management of Duchenne Myopathy in Assiut University Children Hospital
Who cites it
289 citing papers in PubMed.
- Development and characterization of red seabream (Pagrus major) muscle satellite cell lines for cultivated seafood: highlighting serum reduction and microcarrier expansion.In vitro cellular & developmental biology. Animal · 2026Article
- Muscle-specific ERRγ activation mitigates muscle atrophy after ACL injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Progress of mesenchymal stem cells affecting extracellular matrix metabolism in the treatment of female stress urinary incontinence.Stem cell research & therapy · 2025Review
- Regional Gene Therapy for Bone Tissue Engineering: A Current Concepts Review.Bioengineering (Basel, Switzerland) · 2025Review
- Resident vascular Sca1iScience · 2024Article
- Stem Cells and Bone Tissue Engineering.Life (Basel, Switzerland) · 2024Review
- Article
- Sex as a Critical Variable in Basic and Pre-Clinical Studies of Fibrodysplasia Ossificans Progressiva.Biomolecules · 2024Article
- Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.Frontiers in pharmacology · 2024Article
- Review
- Differentiation Capacity of Porcine Skeletal Muscle-Derived Stem Cells as Intermediate Species between Mice and Humans.International journal of molecular sciences · 2023Article
- Hox11-expressing interstitial cells contribute to adult skeletal muscle at homeostasis.Development (Cambridge, England) · 2023Article
- Bioprinted Notch ligand to function as stem cell niche improves muscle regeneration in dystrophic muscle.International journal of bioprinting · 2023Article
- Flow Cytometer Analyses, Isolation, and Staining of Murine Muscle Satellite Cells.Methods in molecular biology (Clifton, N.J.) · 2023Article
- The role of the aging microenvironment on the fate of PDGFRβ lineage cells in skeletal muscle repair.Stem cell research & therapy · 2022Article
- Laminin-221-derived recombinant fragment facilitates isolation of cultured skeletal myoblasts.Regenerative therapy · 2022Article
- Human MuStem cells repress T-cell proliferation and cytotoxicity through both paracrine and contact-dependent pathways.Stem cell research & therapy · 2022Article
- Fli1 Promotes Vascular Morphogenesis by Regulating Endothelial Potential of Multipotent Myogenic Progenitors.Circulation research · 2021Article
- Sca1 marks a reserve endothelial progenitor population that preferentially expand after injury.Cell discovery · 2021Article
- Cellularized small-caliber tissue-engineered vascular grafts: looking for the ultimate gold standard.NPJ Regenerative medicine · 2021Review
229 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Three populations of myogenic cells were isolated from normal mouse skeletal muscle based on their adhesion characteristics and proliferation behaviors. Although two of these populations displayed satellite cell characteristics, a third population of long-time proliferating cells expressing hematopoietic stem cell markers was also identified. This third population comprises cells that retain their phenotype for more than 30 passages with normal karyotype and can differentiate into muscle, neural, and endothelial lineages both in vitro and in vivo. In contrast to the other two populations of myogenic cells, the transplantation of the long-time proliferating cells improved the efficiency of muscle regeneration and dystrophin delivery to dystrophic muscle. The long-time proliferating cells' ability to proliferate in vivo for an extended period of time, combined with their strong capacity for self-renewal, their multipotent differentiation, and their immune-privileged behavior, reveals, at least in part, the basis for the improvement of cell transplantation. Our results suggest that this novel population of muscle-derived stem cells will significantly improve muscle cell-mediated therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.