Evidence map›Paper›PMID 12019123›Full record

Trial reportAntimicrobial agents and chemotherapy2002

Lack of pharmacokinetic interaction between the oral anti-influenza prodrug oseltamivir and aspirin.

Charles Oo, Joanne Barrett, Albert Dorr, Baolian Liu, Penelope Ward

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Antimicrobial agents and chemotherapy, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Charles OoF. Hoffman-La Roche, Nutley, New Jersey 07110, USA. charles.oo@roche.com
Joanne Barrett
Albert Dorr
Baolian Liu
Penelope Ward
La Roche College · USCenter for Global Development · USGlaxoSmithKline (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twelve volunteers completed a two-sequence, three-way crossover study of a single 900-mg aspirin dose and multiple doses of 75 mg of oseltamivir in the absence and presence of 900 mg of aspirin. The plasma and urine results demonstrated no pharmacokinetic interaction between oseltamivir and aspirin.

Indexed as

AcetamidesAdultAnti-Inflammatory Agents, Non-SteroidalAntiviral AgentsAspirinCross-Over StudiesDrug InteractionsFemaleHippuratesHumansMaleOseltamivirProdrugsSalicylic AcidAcetamidesAnti-Inflammatory Agents, Non-SteroidalAntiviral AgentsAspirinHippuratesOseltamivirProdrugsSalicylic Acidsalicylurate

Identifiers

PMID12019123
PMCPMC127254
OpenAlexW2163854125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.