Evidence map›Paper›PMID 1201331›Full record

ArticleBiophysical journal1975

Rapid changes in intracellular free calcium concentration. Detection by metallochromic indicator dyes in squid giant axon.

J E Brown, L B Cohen, P De Weer, L H Pinto, W N Ross, B M Salzberg

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 1975. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 121 citations in OpenAlex.

  1. Water-Soluble Molecular Wires for Membrane Potential Imaging.Angewandte Chemie (International ed. in English) · 2025
    Article
  2. Review
  3. Mapping light distribution in the brain via MRI.Nature biomedical engineering · 2023
    Article
  4. CaeLife · 2020
    Article
  5. Article
  6. Imaging and analysis of genetically encoded calcium indicators linking neural circuits and behaviors.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2019
    Review
  7. Article
  8. Article
  9. Review
  10. Advances in two photon scanning and scanless microscopy technologies for functional neural circuit imaging.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2017
    Article
  11. A Bright and Fast Red Fluorescent Protein Voltage Indicator That Reports Neuronal Activity in Organotypic Brain Slices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Article
  12. Article
  13. Review
  14. Article
  15. Article
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  17. Article
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  19. Review
  20. Imaging input and output dynamics of neocortical networks in vivo: exciting times ahead.Proceedings of the National Academy of Sciences of the United States of America · 2005
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

J E Brown
L B Cohen
P De Weer
L H Pinto
W N Ross
B M Salzberg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The metallochromic indicator dyes, arsenazo III and chlorophosphonazo III, were used in squid giant axons to detect rapidly the very small influxes of calcium that occur as a result of changes of membrane potential.

Indexed as

AnimalsAxonsCalciumColoring AgentsDecapodiformesIndicators and ReagentsMembrane PotentialsCalciumColoring AgentsIndicators and Reagents

Identifiers

PMID1201331
PMCPMC1334796
OpenAlexW2087019284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.