Evidence map›Paper›PMID 12011025›Full record

ArticleInfection and immunity2002

Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus.

Paula Sundstrom, Jim E Cutler, Janet F Staab

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 115 citations in OpenAlex.

  1. mBio · 2025
    Article
  2. Article
  3. Article
  4. Development and Use of a Monoclonal Antibody Specific for theFrontiers in cellular and infection microbiology · 2022
    Article
  5. Review
  6. Article
  7. CRISPR-Based Genetic Manipulation ofFrontiers in genome editing · 2020
    Review
  8. Article
  9. Synergistic Effect of Quinic Acid Derived FromFrontiers in microbiology · 2018
    Article
  10. Review
  11. Pathogenesis of Candida albicans biofilm.Pathogens and disease · 2016
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Paula SundstromDepartment of Molecular Virology, The Ohio State University College of Medicine and Public Health, Columbus, Ohio 43210, USA. sundstrom.1@osu.edu
Jim E Cutler
Janet F Staab
The Ohio State University · USMontana State University · US

Funding

PHOSPHOMANNOPROTEIN ADHESIN AS A VACCINE CANDIDATEP01AI037194 · NIAID · LA BIOMED RES INST/ HARBOR UCLA MED CTR · PI EDWARDS, JOHN E. · 1995 to 2003
$3.6M
PROTEINS OF CANDIDA ALBICANS--AN AIDS RELATED PATHOGENR01DE011375 · NIDCR · OHIO STATE UNIVERSITY · PI SUNDSTROM, PAULA · 1994 to 2007
$2.4M
CANDIDA ALBICANS SURFACE ANTIGENSR01AI024912 · NIAID · MONTANA STATE UNIVERSITY (BOZEMAN) · PI CUTLER, JIM E. · 1988 to 2006
$2.0M
NIAID NIH HHS P01 AI037194NIAID NIH HHS P01 AI37194NIAID NIH HHS R01 AI024912NIAID NIH HHS R01AI24912NIDCR NIH HHS R01 DE011375NIDCR NIH HHS R01 DE11375-05A2
6 · The paper itself

Abstract

Previous evaluation of HWP1 in systemic candidiasis in CBA/J mice was done with Candida albicans strains with differing genetic locations of URA3 as a result of Ura-blaster mutagenesis. In this study, the presence of HWP1 and the location of URA3 contributed to the severity of murine systemic candidiasis in BALB/c mice.

Indexed as

AnimalsBiomarkersCandida albicansCandidiasisDisease Models, AnimalFungal ProteinsGenes, FungalMembrane GlycoproteinsMiceMice, Inbred BALB CPhosphopyruvate HydrataseBiomarkersEno1 protein, mouseFungal ProteinsHWP1 protein, Candida albicansMembrane GlycoproteinsPhosphopyruvate Hydratase

Identifiers

PMID12011025
PMCPMC128023
OpenAlexW2130521604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.