Evidence map›Paper›PMID 12001220›Full record

ArticleThe Anatomical record2002

Approaches to studying cellular signaling: a primer for morphologists.

Kathy Kay Hartford Svoboda, Wende R Reenstra

Abstract read
In one paragraph

Article in The Anatomical record, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. ROCK inhibitor (Y27632) increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium.Developmental dynamics : an official publication of the American Association of Anatomists · 2004
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kathy Kay Hartford SvobodaDepartment of Biomedical Sciences, Texas A & M University System Health Science Center, Baylor College of Dentistry, Dallas 75246, USA. ksvoboda@tambcd.edu
Wende R Reenstra

Funding

BIOLOGY OF THE EMBRYONIC CORNEAL EPITHELIUMR01EY008886 · NEI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI SVOBODA, KATHY KAY · 1991 to 2001
$459k
NEI NIH HHS EY08886NEI NIH HHS R01 EY008886
6 · The paper itself

Abstract

Many research projects will lead to understanding tissue and/or cell responses to extracellular influences either from soluble factors or the surrounding extracellular matrix. These types of investigations will require the understanding of signal transduction. This particular cell biological field has literally exploded with information and new technical approaches in the past 10 years. This article is directed toward investigators interested in using these new approaches to study their systems. An overview of the general principles of signal transduction events including the types of receptors and intracellular signaling events is followed by an introduction to methods for visualizing signal transduction. This is followed by an introduction to biochemical analysis and an example of combining several approaches to understanding a tissue response to extracellular matrix stimulus.

Indexed as

Cell Physiological PhenomenaEducation, MedicalAnatomyBiochemistryHumansIntracellular MembranesProteinsReceptors, Cell SurfaceSignal TransductionProteinsReceptors, Cell Surface

Identifiers

PMID12001220
PMCPMC2862383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.