ArticlePlant molecular biology2002
Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells.
Article in Plant molecular biology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Expression and functional analysis ofFrontiers in plant science · 2022Article
- A novel adenylate isopentenyltransferase 5 regulates shoot branching via the ATTTA motif in Camellia sinensis.BMC plant biology · 2021Article
- Sugar Signaling and Post-transcriptional Regulation in Plants: An Overlooked or an Emerging Topic?Frontiers in plant science · 2020Review
- SAUR36, a small auxin up RNA gene, is involved in the promotion of leaf senescence in Arabidopsis.Plant physiology · 2013Article
- Posttranscriptional control of photosynthetic mRNA decay under stress conditions requires 3' and 5' untranslated regions and correlates with differential polysome association in rice.Plant physiology · 2012Article
- Iron and ROS control of the DownSTream mRNA decay pathway is essential for plant fitness.The EMBO journal · 2012Article
- In silicio expression analysis of PKS genes isolated from Cannabis sativa L.Genetics and molecular biology · 2010Article
- Circadian control of messenger RNA stability. Association with a sequence-specific messenger RNA decay pathway.Plant physiology · 2005Article
- Production of biologically active GM-CSF in sugarcane: a secure biofactory.Transgenic research · 2005Article
- Identification of unstable transcripts in Arabidopsis by cDNA microarray analysis: rapid decay is associated with a group of touch- and specific clock-controlled genes.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- New molecular phenotypes in the dst mutants of Arabidopsis revealed by DNA microarray analysis.The Plant cell · 2001Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The labile SAUR transcripts from higher plants contain a conserved DST sequence in their 3'-untranslated regions. Two copies of a DST sequence from soybean are sufficient to destabilize reporter transcripts in cultured tobacco cells whereas variants bearing mutations in the conserved ATAGAT or GTA regions are inactive. To investigate the potential for conserved recognition components in mammalian and plant cells, we examined the function of this instability determinant in mouse NIH3T3 fibroblasts and tobacco BY2 cells. In fibroblasts, a tetrameric DST element from soybean accelerated deadenylation and decay of a reporter transcript. However, a version mutated in the ATAGAT region was equally effective in this regard, and a tetrameric DST element from Arabidopsis was inactive. In contrast, the soybean DST element was more active as an mRNA instability element than the mutant version and the Arabidopsis element, when tested as tetramers in tobacco cells. Hence, the plant DST element is not recognized in animal cells with the same sequence requirements as in plant cells. Therefore, its mode of recognition appears to be plant-specific.
Indexed as
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Registered trials
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