ArticleThe Journal of infectious diseases2002
Outbreaks of adult gastroenteritis traced to a single genotype of rotavirus.
Article in The Journal of infectious diseases, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 70 citations in OpenAlex.
- Rotavirus Disease and Genotype Diversity in Older Children and Adults in Australia.The Journal of infectious diseases · 2022Article
- Prevalence and Genetic Diversity of Group A Rotavirus Genotypes in Moscow (2019-2020).Pathogens (Basel, Switzerland) · 2021Article
- Impact of rotavirus vaccination on rotavirus genotype distribution and diversity in England, September 2006 to August 2016.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019Article
- Multicenter prospective study on the burden of rotavirus gastroenteritis in children less than 3 years of age in Spain.BMC infectious diseases · 2016Observational
- Changing distribution of age, clinical severity, and genotypes of rotavirus gastroenteritis in hospitalized children after the introduction of vaccination: a single center study in Seoul between 2011 and 2014.BMC infectious diseases · 2016Article
- Effectiveness of Pentavalent Rotavirus Vaccine Against a Diverse Range of Circulating Strains in Nicaragua.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016Article
- Identification of novel bovine group A rotavirus G15P[14] strain from epizootic diarrhea of adult cows by de novo sequencing using a next-generation sequencer.Veterinary microbiology · 2014Article
- Changes in anti-group a rotavirus antibody seroprevalence and levels in the Western Gyeongnam province of Korea over 16 years.Journal of Korean medical science · 2013Article
- Rotavirus within day care centres in Oxfordshire, UK: characterization of partial immunity.Journal of the Royal Society, Interface · 2008Article
- Molecular characterization of a novel bovine group A rotavirus.Veterinary microbiology · 2007Article
- Molecular epidemiology of rotavirus diarrhea among children and adults in Nepal: detection of G12 strains with P[6] or P[8] and a G11P[25] strain.Journal of clinical microbiology · 2006Article
- Diarrhea caused by rotavirus in children less than 5 years of age in Hanoi, Vietnam.Journal of clinical microbiology · 2004Article
- Rotavirus infection in adults.The Lancet. Infectious diseases · 2004Review
Corrections and comments
- Commented on by
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Between November 1998 and December 2000, the Centers for Disease Control and Prevention screened samples from 263 outbreaks of gastroenteritis in the United States and identified 3 that were associated with rotavirus among adults. Rotaviruses from each outbreak were further characterized by reverse-transcription polymerase chain reaction. Surprisingly, all specimens were of serotype G2, a strain that is, as determined by high-stringency hybridization analysis, genetically distinct in all 11 gene segments from the other common rotavirus strains in circulation. The unusual coincidence of identification of only G2 strains in these 3 outbreaks of rotavirus gastroenteritis among adults is similar to results from other studies, in which G2 strains were found in association with more-severe disease in children than other rotavirus serotypes and in association with outbreaks of diarrhea among adults in Japan. Although rotavirus infections in adults are relatively uncommon, which indicates that good overall protective immunity exists, the predominance of G2 strains in outbreaks that have occurred in adults suggests that natural immunity to more common strains does not always provide adequate heterotypic immunity to G2 strains. For the rotavirus vaccines under development, special attention may need to be paid to protection against G2 strains.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.