ArticleDigestive diseases and sciences2002
Porcine ileitis model induced by TNBS-ethanol instillation.
Article in Digestive diseases and sciences, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Impact of electro-acupuncture on EAAT2 and NMDAR-2B expression in goats with visceral hypersensitivity.Heliyon · 2024Article
- Protective effect of sucrose esters from cape gooseberry (Physalis peruviana L.) in TNBS-induced colitis.PloS one · 2024Article
- Electroacupuncture Relieves Visceral Hypersensitivity via Balancing PAR2 and PAR4 in the Descending Pain Modulatory System of Goats.Brain sciences · 2023Article
- Image-Guided Transarterial Directed Delivery of Human Mesenchymal Stem Cells for Targeted Gastrointestinal Therapies in a Swine Model.Journal of vascular and interventional radiology : JVIR · 2019Article
- Comparison of the fecal, cecal, and mucus microbiome in male and female mice after TNBS-induced colitis.PloS one · 2019Article
- A novel model for studying ileitis-induced visceral hypersensitivity in goats.Acta veterinaria Scandinavica · 2016Article
- Visceral pain triggered by traction on the ileocecal ligament with ileitis.Journal of pain research · 2016Article
- Visceral Hypersensitivity Is Provoked by 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Ileitis in Rats.Frontiers in pharmacology · 2016Article
- Quantitative Assessment of Inflammation in a Porcine Acute Terminal Ileitis Model: US with a Molecularly Targeted Contrast Agent.Radiology · 2015Article
- Feasibility of MRI in experimentally induced inflammatory small bowel disease: a pilot study in a porcine model.Digestive diseases and sciences · 2010Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nine young pigs were used to evaluate the ability of an trinitrobenzene sulfonic acid-ethanol (TNBS-EtOH) mixture, in varying combinations, to induce ileitis comparable to that caused by intraintestinal instillation in other species. The distal ileum was accessed via laparotomy in anesthetized animals and the TNBS-EtOH was instilled via hypodermic needle. In three pigs in which the instillate was not held within an ileal segment, there were no ileal lesions noted upon necropsy at two weeks after instillation. In all six pigs in which the instillate was confined to a 10-cm length of distal ileum for 10-15 min, there was definite gross and histologic evidence of severe ileitis upon necropsy at one week after instillation. The histopathology was more consistent with Th-1- than Th-2-mediated inflammation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.