ArticleProceedings of the National Academy of Sciences of the United States of America2002
The global phylogeny of glycolytic enzymes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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42 citing papers in PubMed, 126 citations in OpenAlex.
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- Determination of the genome-scale metabolic network ofFrontiers in bioengineering and biotechnology · 2025Article
- Glycolytic enzymes in non-glycolytic web: functional analysis of the key players.Cell biochemistry and biophysics · 2024Review
- The dance of proteostasis and metabolism: Unveiling the caloristatic controlling switch.Cell stress & chaperones · 2024Review
- The metabolic control of DNA replication: mechanism and function.Open biology · 2023Review
- The evolution of morphological development is congruent with the species phylogeny in the genusFrontiers in microbiology · 2023Article
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- Quantitative Proteomics Reveals that GmENO2 Proteins Are Involved in Response to Phosphate Starvation in the Leaves ofInternational journal of molecular sciences · 2021Article
- Identification and assessment of variable single-copy orthologous (SCO) nuclear loci for low-level phylogenomics: a case study in the genus Rosa (Rosaceae).BMC evolutionary biology · 2019Article
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- Development of a serum-free liquid medium for Bartonella species.Folia microbiologica · 2016Article
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- Exploring microbial dark matter to resolve the deep archaeal ancestry of eukaryotes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Article
- Phylogenomic test of the hypotheses for the evolutionary origin of eukaryotes.Molecular biology and evolution · 2014Article
- The futalosine pathway played an important role in menaquinone biosynthesis during early prokaryote evolution.Genome biology and evolution · 2014Article
- Uniquely localized intra-molecular amino acid concentrations at the glycolytic enzyme catalytic/active centers of Archaea, Bacteria and Eukaryota are associated with their proposed temporal appearances on earth.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2013Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genes encoding the glycolytic enzymes of the facultative endocellular parasite Bartonella henselae have been analyzed phylogenetically within a very large cohort of homologues from bacteria and eukaryotes. We focus on this relative of Rickettsia prowazekii along with homologues from other alpha-proteobacteria to determine whether there have been systematic transfers of glycolytic genes from the presumed alpha-proteobacterial ancestor of the mitochondrion to the nucleus of the early eukaryote. The alpha-proteobacterial homologues representing the eight glycolytic enzymes studied here tend to cluster in well-supported nodes. Nevertheless, not one of these alpha-proteobacterial enzymes is related as a sister clade to the corresponding eukaryotic homologues. Nor is there a close phylogenetic relationship between glycolytic genes from Eucarya and any other bacterial phylum. In contrast, several of the reconstructions suggest that there may have been systematic transfer of sequences encoding glycolytic enzymes from cyanobacteria to some green plants. Otherwise, surprisingly little exchange between the bacterial and eukaryotic domains is observed. The descent of eukaryotic genes encoding enzymes of intermediary metabolism is reevaluated.
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