ArticleThorax2002
An estimate of the contribution of HIV infection to the recent rise in tuberculosis in England and Wales.
Article in Thorax, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Ethnic inequalities in multiple long-term health conditions in the United Kingdom: a systematic review and narrative synthesis.BMC public health · 2023Pooled it
- Can we better understand severe mental illness through the lens of Syndemics?Frontiers in psychiatry · 2022Article
- Factors Influencing the Accuracy of Infectious Disease Reporting in Migrants: A Scoping Review.International journal of environmental research and public health · 2017Article
- Synergistic effects of food insecurity and drug use on medication adherence among people living with HIV infection.Journal of behavioral medicine · 2015Article
- Evaluation of intraspecies interactions in biofilm formation by Methylobacterium species isolated from pink-pigmented household biofilms.Microbes and environments · 2014Article
- AtriplaR/anti-TB combination in TB/HIV patients. Drug in focus.BMC research notes · 2011Article
- The growing impact of HIV infection on the epidemiology of tuberculosis in England and Wales: 1999 2003.Thorax · 2007Article
- Tuberculosis treatment outcome monitoring in England, Wales and Northern Ireland for cases reported in 2001.Journal of epidemiology and community health · 2007Article
- Article
- Impact of immigration and HIV infection on tuberculosis incidence in an area of low tuberculosis prevalence.Epidemiology and infection · 2006Article
- HIV Testing among Canadian Tuberculosis Cases from 1997 to 1998.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2006Article
- Co-infection of Mycobacterium tuberculosis and Mycobacterium leprae in human archaeological samples: a possible explanation for the historical decline of leprosy.Proceedings. Biological sciences · 2005Article
- Molecular analysis of shower curtain biofilm microbes.Applied and environmental microbiology · 2004Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe number of patients with tuberculosis has been increasing slowly in England and Wales since the late 1980s. HIV infection has been a contributory factor to increases in tuberculosis in a number of comparable industrialised countries. This study investigated the extent of tuberculosis and HIV co-infection in England and Wales in 1993 and 1998, and estimated its contribution to the increase in tuberculosis observed during this period.
methodsPatients aged 16-54 years old at diagnosis on the 1993 and 1998 National Tuberculosis Survey databases were matched with those on the HIV/AIDS patient database. A coded process maintained patient confidentiality. Primary outcome measures were the increase between 1993 and 1998 in the numbers with both infections reported and an estimate of the proportion of the increase in tuberculosis during this period attributable to HIV co-infection.
resultsIn 1993 61 (2.2%) tuberculosis patients aged 16-54 years matched with patients reported to the HIV database, increasing to 112 (3.3%) in 1998 (p=0.08; OR 1.35; 95% CI 0.97 to 1.87). Patients co-infected with HIV contributed an estimated 8.5% of the increase in number of tuberculosis patients between 1993 and 1998 nationwide (11% in London). In both years prevalence of co-infection was greatest in London and in patients of white and black African ethnic groups.
conclusionsIn 1998 the number of tuberculosis patients co-infected with HIV in England and Wales, though still small, had nearly doubled since 1993, with most of the increase occurring in London. As HIV infection may be undiagnosed in patients with tuberculosis, and tuberculosis may be unreported in patients with diagnosed HIV infection, the true extent of co-infection will have been underestimated by this study. In addition, constraints in coded matching make it inevitable that some reported co-infections are missed. Routine HIV testing of all patients with tuberculosis should now be considered, particularly in patients of white or black African ethnic origin under 55 years of age.
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