ArticleGenetics2002
Homozygosity and linkage disequilibrium.
Article in Genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Trial
- Joint identity among loci under mutation and regular inbreeding.Theoretical population biology · 2024Article
- Review
- Article
- Localizing and Classifying Adaptive Targets with Trend Filtered Regression.Molecular biology and evolution · 2019Article
- Mathematical Properties of Linkage Disequilibrium Statistics Defined by Normalization of the Coefficient D = pAB - pApB.Human heredity · 2019Article
- Article
- Facial cutaneo-mucosal venous malformations can develop independently of mutation of TEK gene but may be associated with excessive expression of Src and p-Src.Journal of negative results in biomedicine · 2017Article
- Linkage disequilibrium in crossbred and pure line chickens.Genetics, selection, evolution : GSE · 2015Article
- Inferring positive selection in humans from genomic data.Investigative genetics · 2015Article
- Article
- Ecotope-based entomological surveillance and molecular xenomonitoring of multidrug resistant malaria parasites in anopheles vectors.Interdisciplinary perspectives on infectious diseases · 2014Review
- Homozygosity analysis in amyotrophic lateral sclerosis.European journal of human genetics : EJHG · 2013Article
- Contribution of an additive locus to genetic variance when inheritance is multi-factorial with implications on interpretation of GWAS.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013Article
- Article
- Genome-wide scan with nearly 700,000 SNPs in two Sardinian sub-populations suggests some regions as candidate targets for positive selection.European journal of human genetics : EJHG · 2012Article
- Genome-wide analysis of zygotic linkage disequilibrium and its components in crossbred cattle.BMC genetics · 2012Article
- On measures of association among genetic variables.Animal genetics · 2012Article
- Linkage disequilibrium under recurrent bottlenecks.Genetics · 2012Article
- Population structure of hyperinvasive serotype 12F, clonal complex 218 Streptococcus pneumoniae revealed by multilocus boxB sequence typing.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2011Article
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Abstract
We illustrate how homozygosity of haplotypes can be used to measure the level of disequilibrium between two or more markers. An excess of either homozygosity or heterozygosity signals a departure from the gametic phase equilibrium: We describe the specific form of dependence that is associated with high (low) homozygosity and derive various linkage disequilibrium measures. They feature a clear biological interpretation, can be used to construct tests, and are standardized to allow comparison across loci and populations. They are particularly advantageous to measure linkage disequilibrium between highly polymorphic markers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.