ArticleNucleic acids research2002
Two-piece tmRNA in cyanobacteria and its structural analysis.
Article in Nucleic acids research, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Review
- Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen.Nature communications · 2020Article
- Regulatory sRNAs in Cyanobacteria.Frontiers in microbiology · 2018Review
- AccessFold: predicting RNA-RNA interactions with consideration for competing self-structure.Bioinformatics (Oxford, England) · 2016Article
- Trans-translation exposed: understanding the structures and functions of tmRNA-SmpB.Frontiers in microbiology · 2014Review
- Article
- Ecological genomics of marine picocyanobacteria.Microbiology and molecular biology reviews : MMBR · 2009Review
- Escherichia coli tmRNA lacking pseudoknot 1 tags truncated proteins in vivo and in vitro.RNA (New York, N.Y.) · 2009Article
- Structure probing of tmRNA in distinct stages of trans-translation.RNA (New York, N.Y.) · 2007Article
- Evolutionary patterns of non-coding RNAs.Theory in biosciences = Theorie in den Biowissenschaften · 2005Article
- Identification of cyanobacterial non-coding RNAs by comparative genome analysis.Genome biology · 2005Article
- Independent binding sites of small protein B onto transfer-messenger RNA during trans-translation.Nucleic acids research · 2005Article
- Loss of the mRNA-like region in mitochondrial tmRNAs of jakobids.RNA (New York, N.Y.) · 2004Article
- Evolutionary resealing of a split RNA: Reversal of gene permutation.RNA (New York, N.Y.) · 2004Article
- The tmRNA website: reductive evolution of tmRNA in plastids and other endosymbionts.Nucleic acids research · 2004Article
- A third lineage with two-piece tmRNA.Nucleic acids research · 2004Article
- Traffic at the tmRNA gene.Journal of bacteriology · 2003Article
- Descent of a split RNA.Nucleic acids research · 2002Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
tmRNA acts to rescue stalled bacterial ribosomes while encoding a peptide tag added trans-translationally to the nascent peptide, targeting it for proteolysis. The permuted gene structure found in a group of cyanobacteria is shown to produce a two-piece mature tmRNA, as had been observed previously for the independently permuted gene of alpha-proteobacteria. The pieces have been mapped onto the gene sequence and aligned for the permuted cyanobacterial tmRNA sequences, including four novel sequences. Structural probing and base pair co-variations support a secondary structure model in which two pairings in the tRNA-like domain hold the two pieces together, and the coding piece bearing the tag reading frame additionally contains a single transient pseudoknot and three other stem-loops. This represents a dramatic reduction in pseudoknot number from the five present in one-piece cyanobacterial tmRNA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.