ArticleProceedings of the National Academy of Sciences of the United States of America2002
Molecular characterization of meiotic recombination across the 140-kb multigenic a1-sh2 interval of maize.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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71 citing papers in PubMed.
- Enhancing local meiotic crossovers in Arabidopsis and maize through juxtaposition of heterozygous and homozygous regions.Nature plants · 2025Article
- Temporal expression of3 Biotech · 2025Article
- Molecular mechanisms and regulation of recombination frequency and distribution in plants.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- Sequence variations associated with novel purple-pericarp super-sweetcorn compared to its purple-pericarp maize and white super-sweetcorn parents.Molecular genetics and genomics : MGG · 2023Article
- Independent evolution of transposase and TIRs facilitated by recombination betweenProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Profiling and Quantification of Anthocyanins in Purple-Pericarp Sweetcorn and Purple-Pericarp Maize.Molecules (Basel, Switzerland) · 2023Article
- Breaking the tight genetic linkage between the a1 and sh2 genes led to the development of anthocyanin-rich purple-pericarp super-sweetcorn.Scientific reports · 2023Article
- Maize Flavonoid Biosynthesis, Regulation, and Human Health Relevance: A Review.Molecules (Basel, Switzerland) · 2022Review
- Engineering meiotic recombination pathways in rice.Plant biotechnology journal · 2019Review
- Intragenic Meiotic Crossovers Generate Novel Alleles with Transgressive Expression Levels.Molecular biology and evolution · 2018Article
- A Critical Assessment of 60 Years of Maize Intragenic Recombination.Frontiers in plant science · 2018Review
- Where to Cross Over? Defining Crossover Sites in Plants.Frontiers in genetics · 2018Review
- Complexity of genetic mechanisms conferring nonuniformity of recombination in maize.Scientific reports · 2017Article
- Meiotic Crossing Over in Maize Knob Heterochromatin.Genetics · 2017Article
- Prolonged expression of the BX1 signature enzyme is associated with a recombination hotspot in the benzoxazinoid gene cluster in Zea mays.Journal of experimental botany · 2015Article
- High-resolution skim genotyping by sequencing reveals the distribution of crossovers and gene conversions in Cicer arietinum and Brassica napus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- The sh2-R allele of the maize shrunken-2 locus was caused by a complex chromosomal rearrangement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- High-resolution mapping and characterization of qRgls2, a major quantitative trait locus involved in maize resistance to gray leaf spot.BMC plant biology · 2014Article
- Contrasted patterns of crossover and non-crossover at Arabidopsis thaliana meiotic recombination hotspots.PLoS genetics · 2013Article
- Maize RNA polymerase IV defines trans-generational epigenetic variation.The Plant cell · 2013Article
11 more citing papers are in PubMed but not listed here.
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Abstract
The 140-kb a1-sh2 interval of the maize genome contains at least four genes (a1, yz1, x1, and sh2). Partial sequence analysis of two haplotypes has revealed many single nucleotide polymorphisms and InDel polymorphisms, including several large structural polymorphisms. The physical positions of 101 meiotic recombination breakpoints are not distributed uniformly across the interval and are instead concentrated within three recombination hot spots. Two of these recombination hot spots are genic (a1 and yz1) and one is apparently nongenic. The x1 gene is not a recombination hot spot. Thus, these results suggest that not all hot spots are genes and indicate that not all genes are hot spots. Two of the 101 recombination events arose by means of either noncrossover events involving conversion tract lengths of at least 17 kb or double-crossover events. Only one recombination breakpoint mapped to the approximately 80-kb distal portion of the a1-sh2 interval that contains large amounts of repetitive DNA including retrotransposons; in this region the ratio of genetic to physical distance is less than 0.5% of the genome's average. These results establish that the retrotransposon faction of the maize genome is relatively inert recombinationally.
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