ArticleThe Journal of physiology2002
Development of membrane conductance improves coincidence detection in the nucleus laminaris of the chicken.
Article in The Journal of physiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Review
- Kv1 channels regulate variations in spike patterning and temporal reliability in the avian cochlear nucleus angularis.Journal of neurophysiology · 2022Article
- Intrinsic properties of avian interaural level difference sound localizing neurons.Brain research · 2021Article
- Intrinsic physiology of inhibitory neurons changes over auditory development.Journal of neurophysiology · 2018Article
- In vivo matching of postsynaptic excitability with spontaneous synaptic inputs during formation of the rat calyx of Held synapse.The Journal of physiology · 2017Article
- Change in the coding of interaural time difference along the tonotopic axis of the chicken nucleus laminaris.Frontiers in neural circuits · 2015Article
- Asymmetric temporal interactions of sound-evoked excitatory and inhibitory inputs in the mouse auditory midbrain.The Journal of physiology · 2014Article
- Heterogeneous calretinin expression in the avian cochlear nucleus angularis.Journal of the Association for Research in Otolaryngology : JARO · 2014Article
- Glycinergic inhibition tunes coincidence detection in the auditory brainstem.Nature communications · 2014Article
- Activity-dependent and activity-independent development of the axon initial segment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Interplay between low threshold voltage-gated K(+) channels and synaptic inhibition in neurons of the chicken nucleus laminaris along its frequency axis.Frontiers in neural circuits · 2014Article
- Activation of metabotropic glutamate receptors improves the accuracy of coincidence detection by presynaptic mechanisms in the nucleus laminaris of the chick.The Journal of physiology · 2013Article
- Intrinsic firing properties in the avian auditory brain stem allow both integration and encoding of temporally modulated noisy inputs in vitro.Journal of neurophysiology · 2012Article
- Short-term synaptic plasticity and intensity coding.Hearing research · 2011Review
- Preparation and culture of chicken auditory brainstem slices.Journal of visualized experiments : JoVE · 2011Article
- Development of glutamatergic synaptic transmission in binaural auditory neurons.Journal of neurophysiology · 2010Article
- Tonotopic tuning in a sound localization circuit.Journal of neurophysiology · 2010Article
- Regulation of glutamatergic and GABAergic neurotransmission in the chick nucleus laminaris: role of N-type calcium channels.Neuroscience · 2009Article
- Impact of synaptic depression on spike timing at the endbulb of Held.Journal of neurophysiology · 2009Article
- Control of a depolarizing GABAergic input in an auditory coincidence detection circuit.Journal of neurophysiology · 2009Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Coincidence detection at the nucleus laminaris (NL) of a chicken was improved between embryos (embryonic days (E) 16 and 17) and chicks (post-hatch days (P) 2-7) in slice preparations. Electrical stimuli were applied bilaterally to the projection fibres to the NL at various intervals. The response window corresponding to the temporal separation of electrical stimuli that resulted in half-maximal firing probability was adopted as the measure of coincidence detection, and was narrower in chicks (1.4 ms) than in embryos (3.9 ms). Between these two ages, the membrane time constant of NL neurons was reduced from 18.4 to 3.2 ms and the membrane conductance was increased 5-fold, while no difference was measured in the input capacitance. Evoked EPSCs decayed slightly faster in chicks, while the size and the time course of miniature EPSCs were unchanged. Action potentials had lower thresholds and larger after-hyperpolarization in chicks than in embryos. Dendrotoxin-I depolarized cells and increased their input resistance significantly at both ages, eliminated the after-hyperpolarization, and delayed the decay phase of action potentials, indicative of the expression of low-threshold K(+) channels. Cs(+) hyperpolarized the cells, increased the input resistance and eliminated sags during hyperpolarization at both ages, while the hyperpolarization sag was affected by neither Ba(2+) nor TEA. These data indicate the expression of hyperpolarization-activated cation channels. Between these two ages, the maximum conductance of low-threshold K(+) channels increased 4-fold to about 16 nS, and hyperpolarization-activated channels increased 6-fold to about 10 nS. Improvement of coincidence detection correlated with the acceleration of the EPSP time course as a result of the increase of these conductances.
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