Evidence map›Paper›PMID 11953414›Full record

ArticleInfection and immunity2002

Genomic analysis of the F3031 Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius by PCR-based subtractive hybridization.

Laura M Smoot, Deanna D Franke, Glen McGillivary, Luis A Actis

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Genomic signatures of hybridization betweenEcology and evolution · 2024
    Article
  2. Article
  3. Article
  4. Genome dynamics in major bacterial pathogens.FEMS microbiology reviews · 2009
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laura M SmootDepartment of Microbiology, Miami University, Oxford, Ohio 45056, USA.
Deanna D Franke
Glen McGillivary
Luis A Actis
Miami University · US

Funding

GENETICS OF H. AEGYPTIUS BRAZILIAN PURPURIC FEVER CLONER15AI044776 · NIAID · MIAMI UNIVERSITY OXFORD · PI ACTIS, LUIS A. · 2000 to 2000
$105k
IRON AQUISITION BY HAEMOPHILUS AEGYPTIUSR15AI037781 · NIAID · MIAMI UNIVERSITY OXFORD · PI ACTIS, LUIS A. · 1995 to 1995
–
NIAID NIH HHS R15AI37781-01NIAID NIH HHS R15AI44776
6 · The paper itself

Abstract

PCR-based subtractive genome hybridization produced clones harboring inserts present in Brazilian purpuric fever (BPF) prototype strain F3031 but absent in noninvasive Haemophilus influenzae biogroup aegyptius isolate F1947. Some of these inserts have no matches in the GenBank database, while others are similar to genes encoding either known or hypothetical proteins. One insert represents a 2.3-kb locus with similarity to a Thermotoga maritima hypothetical protein, while another is part of a 7.6-kb locus that contains predicted genes encoding hypothetical, phage-related, and carotovoricin Er-like proteins. The presence of DNA related to these loci is variable among BPF isolates and nontypeable H. influenzae strains, while neither of them was detected in strains of types a to f. The data indicate that BPF-causing strain F3031 harbors unique chromosomal regions, most of which appear to be acquired from unrelated microbial sources.

Indexed as

Genome, BacterialBase SequenceBrazilChromosome MappingCloning, MolecularFeverGene LibraryHaemophilus influenzaeHumansMolecular Sequence DataPolymerase Chain ReactionPurpura

Identifiers

PMID11953414
PMCPMC127918
OpenAlexW2075908199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.