ReviewGut2002
Cyclooxygenase inhibition: between the devil and the deep blue sea.
Review in Gut, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 8 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Diclofenac for acute postoperative pain in children.The Cochrane database of systematic reviews · 2023Pooled it
- Single-dose intravenous ibuprofen for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2021Pooled it
- Single-dose intravenous ketorolac for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2021Pooled it
- Single-dose intravenous diclofenac for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2018Pooled it
- Single dose dipyrone (metamizole) for acute postoperative pain in adults.The Cochrane database of systematic reviews · 2016Pooled it
- Nonsteroidal anti-inflammatory drugs, gastroprotection, and benefit-risk.Pain practice : the official journal of World Institute of Pain · 2014Pooled it
- WITHDRAWN: Single dose dipyrone for acute postoperative pain.The Cochrane database of systematic reviews · 2013Pooled it
- Single dose dipyrone for acute postoperative pain.The Cochrane database of systematic reviews · 2010Pooled it
- Comparative Analysis of Ketorolac and Parecoxib for Postoperative Pain Management in Uvulopalatopharyngoplasty.Journal of clinical medicine · 2024Article
- Protein Lipoxidation: Basic Concepts and Emerging Roles.Antioxidants (Basel, Switzerland) · 2021Review
- Analgesic Efficacy of Firocoxib, a Selective Inhibitor of Cyclooxygenase 2, in a Mouse Model of Incisional Pain.Journal of the American Association for Laboratory Animal Science : JAALAS · 2015Article
- Antiplatelet agents in clinical practice and their haemorrhagic risk.Blood transfusion = Trasfusione del sangue · 2013Review
- Nonsteroidal anti-inflammatory drugs and their risk: a story still in development.Arthritis research & therapy · 2013Article
- The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein.Arthritis research & therapy · 2006Article
- COX-2 inhibitors as adjunctive therapy in schizophrenia: rationale for use and evidence to date.CNS drugs · 2005Review
- Peroxisome proliferator-activated receptor gamma activation counters the detrimental effect of Helicobacter pylori lipopolysaccharide on gastric mucin synthesis.Inflammopharmacology · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-steroidal anti-inflammatory drugs (NSAIDs) account for more reports of drug related toxicity than any other class of drugs. Their most widely recognised adverse effects are on the gastrointestinal tract. They cause acute erosions and chronic ulcers that result in hospitalisation and death because of ulcer bleeding and perforation. Between them, aspirin and non-aspirin NSAIDs may account for more than half of all episodes of ulcer bleeding and perforation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.