Evidence map›Paper›PMID 11952093›Full record

ReviewMolecular and cellular biochemistry2002

Soluble guanylate cyclases in the retina.

Ari Sitaramayya

Abstract readReview
PubMed
In one paragraph

Review in Molecular and cellular biochemistry, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ari SitaramayyaEye Research Institute, Oakland University, Rochester, MI 48309-4480, USA.
Smith-Kettlewell Eye Research Institute · US

Funding

VISION RESEARCHP30EY005230 · NEI · OAKLAND UNIVERSITY · PI BLANKS, JANET C · 1985 to 1999
–
NEI NIH HHS EY 05230NEI NIH HHS EY 07158
6 · The paper itself

Abstract

Soluble guanylate cyclase catalyzes the formation of cyclic GMP using GTP as substrate. It is now well established that soluble guanylate cyclase is highly activated by nitric oxide, and that many of the effects of nitric oxide on various cells and tissues are mediated through increased production of cyclic GMP. This review discusses the evidence for the presence of soluble guanylate cyclases in different classes of cells in vertebrate retina and the role of these enzymes in retinal physiology. It is concluded that the enzyme is present in nearly every class of cells in the retina and that it may be involved in signal transmission between some cells and in the modulation of signal transmission between others.

Indexed as

AnimalsCell CommunicationCell DeathGuanylate CyclaseHumansNeuronsReceptors, Cytoplasmic and NuclearRetinaSignal TransductionSoluble Guanylyl CyclaseGuanylate CyclaseReceptors, Cytoplasmic and NuclearSoluble Guanylyl Cyclase

Identifiers

PMID11952093
OpenAlexW1547350408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.