Evidence map›Paper›PMID 11951969›Full record

ArticleJournal of the American Society for Mass Spectrometry2002

A general method for precalculation of parameters for sustained off resonance irradiation/collision-induced dissociation.

Ekaterina Mirgorodskaya, Peter B O'Connor, Catherine E Costello

Abstract read
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In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Sphingolipidomics: methods for the comprehensive analysis of sphingolipids.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2009
    Review
  4. Article
  5. Probing the gas-phase folding kinetics of peptide ions by IR activated DR-ECD.Journal of the American Society for Mass Spectrometry · 2008
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Reverse transcription-associated dephosphorylation of hepadnavirus nucleocapsids.Proceedings of the National Academy of Sciences of the United States of America · 2005
    Article
  11. Article
  12. Article
  13. Resonant excitation in a low-pressure linear ion trap.Journal of the American Society for Mass Spectrometry · 2003
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ekaterina MirgorodskayaMass Spectrometry Resource, Department of Biochemistry, Boston University School of Medicine, Massachusetts 02118-2526, USA.
Peter B O'Connor
Catherine E Costello

Funding

XI INTERNATIONAL SYMPOSIUM ON AMYLOIDOSISP41RR010888 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ZAIA, JOSEPH · 1996 to 2011
$18.6M
NCRR NIH HHS P41 RR10888
6 · The paper itself

Abstract

Sustained off resonance irradiation (SORI) collision-induced dissociation (CID) is a commonly used method of collisionally activating ions for fragmentation in Fourier transform mass spectrometric experiments. To achieve the degree of fragmentation desired, both the irradiation frequency and amplitude must be optimized. This is a time-consuming procedure, particularly when the m/z values of the precursor ions vary over a broad range. We present an approach that simplifies this optimization by precalculating the irradiation frequency of the ions to be fragmented as a constant percentage of the reduced cyclotron frequency. Using this approach, the optimal amplitude was found to be significantly less dependent on the m/z value of the precursor ion, and therefore required little or no adjustment. This method considerably simplified optimization of SORI-CID for analysis of carbohydrates, glycoconjugates, and peptides over the mass range m/z 300-3500, requiring optimization of only a single experimental parameter, the irradiation amplitude, and only for the first MS/MS stage.

Indexed as

AlgorithmsAmino Acid SequenceFourier AnalysisGlycolipidsGlycoproteinsGlycosphingolipidsIndicators and ReagentsMolecular Sequence DataOligosaccharidesPeptidesSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationGlycolipidsGlycoproteinsGlycosphingolipidsIndicators and ReagentsOligosaccharidesPeptides

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.