ArticleProceedings. Biological sciences2002
A possible role for imprinted genes in inbreeding avoidance and dispersal from the natal area in mice.
Article in Proceedings. Biological sciences, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Mom genes and dad genes: genomic imprinting in the regulation of social behaviors.Epigenomics · 2025Review
- Impact of external odor on self-grooming of lesser flat-headed bats,Ecology and evolution · 2019Article
- Drivers of sex ratio bias in the eastern bongo: lower inbreeding increases the probability of being born male.Proceedings. Biological sciences · 2019Article
- Intragenomic conflict over bet-hedging.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- No speed dating please! Patterns of social preference in male and female house mice.Frontiers in zoology · 2017Article
- New Perspectives on Genomic Imprinting, an Essential and Multifaceted Mode of Epigenetic Control in the Developing and Adult Brain.Annual review of neuroscience · 2016Review
- Article
- Genomic imprinting and the social brain.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006Review
- Imprinted Nesp55 influences behavioral reactivity to novel environments.Molecular and cellular biology · 2005Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The expression of a subset of mammalian genes is subject to parent of origin effects (POE), most of which can be explained by genomic imprinting. Analysis of mutant animals has demonstrated that a number of imprinted genes influence brain development and behaviour. Here we provide evidence for POE on olfactory related behaviour and sensitivity to maternal odour cues. This was investigated by examining the odour preference behaviour of reciprocal cross F(1) mice made by embryo transfer to genetically unrelated foster parents. We determined that both adult males and females show an avoidance of female urinary odours of their genetic maternal but not paternal origin. This was found not to be due to any previous exposure to these odours or due to self-learning, but may be related to direct effects on the olfactory system, as reciprocal F(1) males show differential sensitivity to female odour cues. Currently the most robust theory to explain the evolution of imprinting is the conflict hypothesis that focuses on maternal resource allocation to the developing foetus. Kinship considerations are also likely to be important in the selection of imprinted genes and we discuss our findings within this context, suggesting that imprinted genes act directly on the olfactory system to promote post-weaning dispersal from the natal area.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.