Evidence map›Paper›PMID 11932427›Full record

ArticleJournal of virology2002

The carboxy terminus of simian virus 40 large T antigen is required to disrupt the yeast cell cycle.

Sheara W Fewell, Dena M Markle, Jeffrey L Brodsky

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Contribution of yeast models to virus research.Applied microbiology and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sheara W FewellDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260,USA.
Dena M Markle
Jeffrey L Brodsky
University of Pittsburgh · US

Funding

CHAPERONE ACTIVITY OF SV40 LARGE T ANTIGENF32CA083270 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FEWELL, SHEARA W · 1999 to 2002
$86k
NCI NIH HHS 1 F32 CA 83270-01NCI NIH HHS F32 CA083270
6 · The paper itself

Abstract

Wild-type and J domain mutant simian virus 40 large T antigens alter the cell cycle and bud morphology of Saccharomyces cerevisiae. In contrast, yeast cells expressing mutant T antigen lacking the carboxy-terminal 150 aa exhibit normal morphology, indicating that this region of T antigen is required for cell cycle disruption.

Indexed as

Antigens, Polyomavirus TransformingCell CycleSaccharomyces cerevisiaeSimian virus 40Antigens, Polyomavirus Transforming

Identifiers

PMID11932427
PMCPMC155092
OpenAlexW2131299620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.