ArticleCurrent infectious disease reports2002
Entamoeba histolytica: Clinical Update and Vaccine Prospects.
Article in Current infectious disease reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 9 citations in OpenAlex.
- Intestinal amebiasis: a concerning cause of acute gastroenteritis among hospitalized lebanese children.North American journal of medical sciences · 2013Article
- Bioinformatic analysis of Entamoeba histolytica SINE1 elements.BMC genomics · 2010Article
- Prevalence and characters of Entamoeba histolytica infection in Saudi infants and children admitted with diarrhea at 2 main hospitals at South Jeddah: a re-emerging serious infection with unusual presentation.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Amebiasis is extraordinarily common in children of the developing world. This realization has come from application of diagnostic techniques that distinguish the nonpathogenic parasite Entamoeba dispar from Entamoeba histolytica. E. histolytica infection is found in children with dysentery, diarrhea, and in many cases in children with no gastrointestinal symptoms. Genetically distinct strains of E. histolytica exist but evidence is too preliminary to judge if some strains are more virulent than others. A provocative study from Tanzania has shown that pregnant women with HIV infection who are coinfected with E. histolytica are at greater risk of delivering a low birth weight infant. Perhaps the most exciting new data is the identification of acquired immunity to recurrent E. histolytica infection. Acquired immunity is linked to a mucosal immune response against a major virulence factor of the parasite, a Gal/GalNAc lectin responsible for adherence and killing of the host. Prospects for a vaccine are thus brightening at the same time that the true burden of disease is comprehended.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.