Evidence map›Paper›PMID 11923346›Full record

ArticleJournal of clinical microbiology2002

Mitochondrial telomeres as molecular markers for identification of the opportunistic yeast pathogen Candida parapsilosis.

Jozef Nosek, L'ubomír Tomáska, Adriana Rycovská, Hiroshi Fukuhara

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. The first established microsatellite markers to distinguishJournal of clinical microbiology · 2023
    Article
  2. Article
  3. Article
  4. Candida parapsilosis: from Genes to the Bedside.Clinical microbiology reviews · 2019
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Evaluation of matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry for identification of Candida parapsilosis, C. orthopsilosis and C. metapsilosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Candida parapsilosis, an emerging fungal pathogen.Clinical microbiology reviews · 2008
    Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jozef NosekDepartment of Biochemistry, Faculty of Natural Sciences, Comenius University, 84215 Bratislava, Slovakia. nosek@fns.uniba.sk
L'ubomír Tomáska
Adriana Rycovská
Hiroshi Fukuhara

Funding

Studies of Telomere Structure Using Yeast Model SystemsR03TW005654 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GRIFFITH, JACK D · 2001 to 2008
$227k
FIC NIH HHS 1-R03-TW05654-01FIC NIH HHS R03 TW005654
6 · The paper itself

Abstract

Recent studies have demonstrated that a large number of organisms carry linear mitochondrial DNA molecules possessing specialized telomeric structures at their ends. Based on this specific structural feature of linear mitochondrial genomes, we have developed an approach for identification of the opportunistic yeast pathogen Candida parapsilosis. The strategy for identification of C. parapsilosis strains is based on PCR amplification of specific DNA sequences derived from the mitochondrial telomere region. This assay is complemented by immunodetection of a protein component of mitochondrial telomeres. The results demonstrate that mitochondrial telomeres represent specific molecular markers with potential applications in yeast diagnostics and taxonomy.

Indexed as

CandidaCandidiasisDNA, FungalDNA, MitochondrialGenetic MarkersHumansImmunoblottingOpportunistic InfectionsPolymerase Chain ReactionRNA, Ribosomal, 18SSequence Analysis, DNASpecies SpecificityTelomereDNA, FungalDNA, MitochondrialGenetic MarkersRNA, Ribosomal, 18S

Identifiers

PMID11923346
PMCPMC140342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.