Goal-directed therapy for severe sepsis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a meta-analysis.Critical care medicine · 2008
   Pooled it
2. Improving the Recognition of, and Response to In-Hospital Sepsis.Current infectious disease reports · 2016
   Review
3. From macrohemodynamic to the microcirculation.Critical care research and practice · 2013
   Article
4. Sepsis: a review for the neurohospitalist.The Neurohospitalist · 2012
   Article
5. Surviving sepsis: going beyond the guidelines.Annals of intensive care · 2011
   Article
6. Wanted: early goal-directed therapy for septic shock--dead or alive, but not critically ill!Intensive care medicine · 2010
   Article
7. When less is more in the intensive care unit; lessons learned.Bosnian journal of basic medical sciences · 2009
   Article
8. Novel pharmacologic approaches to the management of sepsis: targeting the host inflammatory response.Recent patents on inflammation & allergy drug discovery · 2009
   Review
9. Why are clinicians not embracing the results from pivotal clinical trials in severe sepsis? A bayesian analysis.PloS one · 2008
   Article
10. The optimal endpoint of resuscitation in trauma patients.Critical care (London, England) · 2003
    Article

Corrections and comments

• Comment on
  Early goal-directed therapy in the treatment of severe sepsis and septic shock.2001

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as