Evidence map›Paper›PMID 11919022›Full record

ReviewJournal of feline medicine and surgery1999

The role of polymerase chain reaction and its newer developments in feline medicine.

H Lutz, C Leutenegger, R Hofmann-Lehmann

Abstract readReview
In one paragraph

Review in Journal of feline medicine and surgery, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Aetiology of corneal ulcers assume FHV-1 unless proven otherwise.Journal of feline medicine and surgery · 2010
    Review
  3. Review
  4. Ocular manifestations of feline herpesvirus.Journal of feline medicine and surgery · 2001
    Review
  5. PCR and feline medicine.Journal of feline medicine and surgery · 1999
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

H LutzClinical Laboratory Department of Veterinary Internal Medicine, University of Zürich, Switzerland. hanslutz@vetklinik.unizh.ch
C Leutenegger
R Hofmann-Lehmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We give a brief overview on the principles of the polymerase chain reaction (PCR), reverse transcriptase PCR (RT-PCR), quantitative competitive PCR and real-time PCR (TaqMan technology). The literature dealing with PCR and its role in the diagnosis, pathogenesis and research of infectious diseases of the domestic cat is reviewed. Cross-contaminations which occasionally occur during handling of amplified DNA may be an important problem in the PCR laboratory. In many infectious diseases, PCR results are difficult to interpret as their predictive positive and negative values are not always known. Newer assays, such as TaqMan procedures, are becoming increasingly reliable and cost-effective. It can be expected that additional knowledge on how to interpret PCR results will soon be available.

Indexed as

AnimalsCat DiseasesCatsPolymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionVeterinary Medicine

Identifiers

PMID11919022
PMCPMC7129993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.