ReviewCurrent allergy and asthma reports2002
Staphylococcus aureus superantigens and airway disease.
Review in Current allergy and asthma reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Phenotypic Remodeling of γδ T Cells in Non-Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis.Medicina (Kaunas, Lithuania) · 2025Article
- Contribution of Infectious Agents to the Development of Celiac Disease.Microorganisms · 2021Review
- Novel Treatments and Preventative Strategies Against Food-Poisoning Caused by Staphylococcal Species.Pathogens (Basel, Switzerland) · 2021Review
- Potential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis.American journal of respiratory cell and molecular biology · 2017Article
- Mechanisms of Glucocorticoid Action in Chronic Rhinosinusitis.Allergy, asthma & immunology research · 2015Review
- Chronic Rhinosinusitis and the Coagulation System.Allergy, asthma & immunology research · 2015Review
- Increased expression of factor XIII-A in patients with chronic rhinosinusitis with nasal polyps.The Journal of allergy and clinical immunology · 2013Article
- Excessive fibrin deposition in nasal polyps caused by fibrinolytic impairment through reduction of tissue plasminogen activator expression.American journal of respiratory and critical care medicine · 2013Article
- Glandular mast cells with distinct phenotype are highly elevated in chronic rhinosinusitis with nasal polyps.The Journal of allergy and clinical immunology · 2012Article
- Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Increased expression of the chemokine CCL23 in eosinophilic chronic rhinosinusitis with nasal polyps.The Journal of allergy and clinical immunology · 2011Article
- Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps.The Journal of allergy and clinical immunology · 2010Article
- Association of specific IgE to staphylococcal superantigens with the phenotype of chronic urticaria.Journal of Korean medical science · 2008Article
- Inhalation of Staphylococcus aureus enterotoxin A induces IFN-gamma and CD8 T cell-dependent airway and interstitial lung pathology in mice.Journal of immunology (Baltimore, Md. : 1950) · 2008Article
- Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.The Journal of allergy and clinical immunology · 2008Article
- The relationship between rhinosinusitis and asthma sinusitis.Current allergy and asthma reports · 2006Review
- Intranasal exposure to bacterial superantigens induces airway inflammation in HLA class II transgenic mice.Infection and immunity · 2006Article
- Pathophysiological classification of chronic rhinosinusitis.Respiratory research · 2005Article
- Inflammatory mechanisms underlying the rat pulmonary neutrophil influx induced by airway exposure to staphylococcal enterotoxin type A.British journal of pharmacology · 2005Article
- A murine model of ulcerative colitis: induced with sinusitis-derived superantigen and food allergen.BMC gastroenterology · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Twenty-five percent of the population are permanent carriers of Staphylococcus aureus, possibly producing a variety of toxins with superantigenic properties. Staphylococcal superantigens are a group of high- molecular-weight pyrogenic proteins that have in common an extremely potent stimulatory activity for T-lymphocytes, macrophages, mast cells, eosinophils, and epithelial cells. The role of staphylococcal superantigens in atopic dermatitis has recently been recognized, and new evidence suggests that similar mechanisms may also be relevant in airway disease. This circumstantial evidence is currently limited to rhinitis, sinusitis, and possibly asthma, but may, if supported, open a new understanding of pathomechanisms and therapeutic targets.
Indexed as
Identifiers
11918868What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.