ReviewCurrent allergy and asthma reports2002
Neurology of allergic inflammation and rhinitis.
Review in Current allergy and asthma reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Sphenopalatine ganglion stimulation: a comprehensive evaluation across diseases in randomized controlled trials.Frontiers in neurology · 2024Pooled it
- A simple, innovative way to reduce rhinitis symptoms after sedation during endoscopy.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2011Trial
- Impact of nonpharmaceutical interventions on inflammatory diseases of the nose.Annals of medicine · 2025Article
- Ultrasound guided pulsed radiofrequency neuromodulation of sphenopalatine ganglion treatment for allergic rhinitis in childern: A case report.Clinical case reports · 2024Article
- Tic disorder in allergic rhinitis children and adolescents: a case-control study.BMC pediatrics · 2024Article
- Mutual Influence Between Allergic Rhinitis and Sleep: Factors, Mechanisms, and interventions-A Narrative Review.Nature and science of sleep · 2024Review
- A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction.Brain, behavior, and immunity · 2020Article
- Article
- Sleep Disorders: Is the Trigemino-Cardiac Reflex a Missing Link?Frontiers in neurology · 2017Review
- Pupillometric assessment of autonomic nervous system in children with allergic rhinitis.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2013Article
- Heart rate variability analysis in patients with allergic rhinitis.TheScientificWorldJournal · 2013Article
- Stress-related programming of autonomic imbalance: role in allergy and asthma.Chemical immunology and allergy · 2012Article
- Leukotriene D4 increases the excitability of capsaicin-sensitive nasal sensory nerves to electrical and chemical stimuli.British journal of pharmacology · 2008Article
- Sneeze related area in the medulla: localisation of the human sneezing centre?Journal of neurology, neurosurgery, and psychiatry · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Afferent nerves, derived from the trigeminal ganglion, and postganglionic autonomic nerves, derived from sympathetic and parasympathetic ganglia expressing many different neurotransmitters, innervate the nose. Reflexes that serve to optimize the air-conditioning function of the nose by altering sinus blood flow, or serve to protect the nasal mucosal surface by mucus secretion, vasodilatation, and sneezing, can be initiated by a variety of stimuli, including allergen, cold air, and chemical irritation. Activation of nasal afferent nerves can also have profound effects on respiration, heart rate, blood pressure, and airway caliber (the diving response). Dysregulation of the nerves in the nose plays an integral role in the pathogenesis of allergic rhinitis. Axon reflexes can precipitate inflammatory responses in the nose, resulting in plasma extravasation and inflammatory cell recruitment, while allergic inflammation can produce neuronal hyper-responsiveness. Targeting the neuronal dysregulation in the nose may be beneficial in treating upper airway disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.