Evidence map›Paper›PMID 11918698›Full record

ArticleImmunology2002

A feline CD2 homologue interacts with human red blood cells.

Masayuki Shimojima, Yorihiro Nishimura, Takayuki Miyazawa, Kentaro Kato, Kazuya Nakamura, Yoshihiro Izumiya, Hiroomi Akashi, Yukinobu Tohya

Open access · greenAbstract read
In one paragraph

Article in Immunology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Masayuki ShimojimaDepartment of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Yorihiro Nishimura
Takayuki Miyazawa
Kentaro Kato
Kazuya Nakamura
Yoshihiro Izumiya
Hiroomi Akashi
Yukinobu Tohya
The University of Tokyo · JPOsaka University · JPUniversity of California, Davis · USYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cDNA encoding a feline homologue of CD2 (fCD2) was identified. Several amino acids (aa) important for ligand interaction, molecular folding or signal transduction, found in other mammalian CD2, were found to be highly conserved in the predicted fCD2 aa sequence. fCD2-expressing cells were able to form rosettes with human red blood cells (probably via human CD58), and the rosette formation was inhibited by an anti-fCD2 monoclonal antibody. These results are indicative of the similarity of feline and human CD2 structures. fCD2 was found to be expressed in feline peripheral blood T lymphocytes, monocytes and cultured lymphoid cells.

Indexed as

Amino Acid SequenceAnimalsAntibodies, MonoclonalCatsCD2 AntigensConserved SequenceDNA, ComplementaryErythrocytesHumansMolecular Sequence DataMonocytesRosette FormationSpecies SpecificityT-LymphocytesAntibodies, MonoclonalCD2 AntigensDNA, Complementary

Identifiers

PMID11918698
PMCPMC1782671
OpenAlexW2089782065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.