ArticleBiophysical journal2002
Echinocyte shapes: bending, stretching, and shear determine spicule shape and spacing.
Article in Biophysical journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- A phase-field model for vesicle membranes incorporating area-difference elasticity.PLoS computational biology · 2026Article
- Bending Energy Schemes for Discrete-Spring-Network Structural Modelling of Red Blood Cells.International journal for numerical methods in biomedical engineering · 2025Article
- The Mechanical Properties of Erythrocytes Are Influenced by the Conformational State of Albumin.Cells · 2025Review
- Stomatocyte-discocyte-echinocyte transformations of erythrocyte modulated by membrane-cytoskeleton mechanical properties.Biophysical journal · 2025Article
- Piezo1 Regulation Involves Lipid Domains and the Cytoskeleton and Is Favored by the Stomatocyte-Discocyte-Echinocyte Transformation.Biomolecules · 2023Article
- Effective cell membrane tension protects red blood cells against malaria invasion.PLoS computational biology · 2023Article
- Coupling of nematic in-plane orientational ordering and equilibrium shapes of closed flexible nematic shells.Scientific reports · 2023Article
- Small Cellular Particles from European Spruce Needle Homogenate.International journal of molecular sciences · 2023Article
- Predicting optoacoustic spectral behaviour of human erythrocytes, stomatocytes and echinocytes using a modified Green's function method.European biophysics journal : EBJ · 2022Article
- On the Role of Curved Membrane Nanodomains, and Passive and Active Skeleton Forces in the Determination of Cell Shape and Membrane Budding.International journal of molecular sciences · 2021Article
- Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation.PLoS computational biology · 2020Article
- Theoretical Bases for the Role of Red Blood Cell Shape in the Regulation of Its Volume.Frontiers in physiology · 2020Review
- Normal red blood cells' shape stabilized by membrane's in-plane ordering.Scientific reports · 2019Article
- Physical Processes in Polymeric Filters Used for Dialysis.Polymers · 2019Review
- Numerical Model for the Determination of Erythrocyte Mechanical Properties and Wall Shear StressFrontiers in physiology · 2019Article
- A coarse-grained red blood cell membrane model to study stomatocyte-discocyte-echinocyte morphologies.PloS one · 2019Article
- The Blood Bag Plasticizer Di-2-Ethylhexylphthalate Causes Red Blood Cells to Form Stomatocytes, Possibly by Inducing Lipid Flip-Flop.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2018Article
- Modeling Membrane Curvature Generation due to Membrane⁻Protein Interactions.Biomolecules · 2018Review
- Erythrocyte Aging, Protection via Vesiculation: An Analysis Methodology via Oscillatory Flow.Frontiers in physiology · 2018Article
- A cdk1 gradient guides surface contraction waves in oocytes.Nature communications · 2017Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We study the shapes of human red blood cells using continuum mechanics. In particular, we model the crenated, echinocytic shapes and show how they may arise from a competition between the bending energy of the plasma membrane and the stretching/shear elastic energies of the membrane skeleton. In contrast to earlier work, we calculate spicule shapes exactly by solving the equations of continuum mechanics subject to appropriate boundary conditions. A simple scaling analysis of this competition reveals an elastic length Lambda(el), which sets the length scale for the spicules and is, thus, related to the number of spicules experimentally observed on the fully developed echinocyte.
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