ArticleProceedings of the National Academy of Sciences of the United States of America2002
Extreme genome reduction in Buchnera spp.: toward the minimal genome needed for symbiotic life.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
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85 citing papers in PubMed.
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- Comparative genomics of the primary endosymbiont Buchnera aphidicola in aphid hosts and their coevolutionary relationships.BMC biology · 2024Article
- Seasonal wild dance of dual endosymbionts in the pear psyllid Cacopsylla pyricola (Hemiptera: Psylloidea).Scientific reports · 2023Article
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- Physicochemical classification of organisms.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Transitional genomes and nutritional role reversals identified for dual symbionts of adelgids (Aphidoidea: Adelgidae).The ISME journal · 2022Article
- Adaptive Variation ofACS omega · 2021Article
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- Inactivation of genes in oxidative respiration and iron acquisition pathways in pediatric clinical isolates of Small colony variant Enterobacteriaceae.Scientific reports · 2021Article
- Isolation and cultivation of candidate phyla radiationJournal of oral microbiology · 2020Article
- An assessment of genome annotation coverage across the bacterial tree of life.Microbial genomics · 2020Article
- Dynamics of Insect-Microbiome Interaction Influence Host and Microbial Symbiont.Frontiers in microbiology · 2020Review
- SeqDeχ: A Sequence Deconvolution Tool for Genome Separation of Endosymbionts From Mixed Sequencing Samples.Frontiers in genetics · 2019Article
- Multi-scale characterization of symbiont diversity in the pea aphid complex through metagenomic approaches.Microbiome · 2018Article
- Bacteriocyte cell death in the pea aphid/Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Cell-free TXTL synthesis of infectious bacteriophage T4 in a single test tube reaction.Synthetic biology (Oxford, England) · 2018Article
25 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
Buchnera is a mutualistic intracellular symbiont of aphids. Their association began about 200 million years ago, with host and symbiont lineages evolving in parallel since that time. During this coevolutionary process, Buchnera has experienced a dramatic decrease of genome size, retaining only essential genes for its specialized lifestyle. Previous studies reported that genome size in Buchnera spp. is very uniform, suggesting that genome shrinkage occurred early in evolution, and that modern lineages retain the genome size of a common ancestor. Our physical mapping of Buchnera genomes obtained from five aphid lineages shows that the genome size is not conserved among them, but has been reduced down to 450 kb in some species. Here we show evidence of six species with a genome size smaller than Mycoplasma genitalium, the smallest bacterial genome reported thus far (580 kb). Our findings strongly suggest that the Buchnera genome is still experiencing a reductive process toward a minimum set of genes necessary for its symbiotic lifestyle.
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