Antigen-specific immunotherapy for autoimmune disease: fighting fire with fire?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

26 citing papers in PubMed.

1. Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man Phase I safety study.Clinical and experimental immunology · 2009
   Trial
2. Antigen-specific immunotherapy with a CD4Nature communications · 2026
   Article
3. Emerging and underrecognized viral triggers of autoimmune inflammatory rheumatic disease flares.Nature reviews. Rheumatology · 2026
   Review
4. A Perspective on Oral Immunotherapeutic Tools and Strategies for Autoimmune Disorders.Vaccines · 2023
   Review
5. Impact of Siglecs on autoimmune diseases.Molecular aspects of medicine · 2023
   Review
6. Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients.Frontiers in immunology · 2022
   Article
7. Linking autoantigen properties to mechanisms of immunity.Advanced drug delivery reviews · 2020
   Review
8. Role of the PD-1/PD-L1 Dyad in the Maintenance of Pancreatic Immune Tolerance for Prevention of Type 1 Diabetes.Frontiers in endocrinology · 2020
   Review
9. Antigen-Drug Conjugates as a Novel Therapeutic Class for the Treatment of Antigen-Specific Autoimmune Disorders.Molecular pharmaceutics · 2019
   Article
10. 14-3-3ζ-A Novel Immunogen Promotes Inflammatory Cytokine Production.Frontiers in immunology · 2019
    Article
11. Bioconjugate Strategies for the Induction of Antigen-Specific Tolerance in Autoimmune Diseases.Bioconjugate chemistry · 2018
    Review
12. Identification of matrix metalloproteinase-12 as a candidate molecule for prevention and treatment of cardiometabolic disease.Molecular medicine (Cambridge, Mass.) · 2016
    Article
13. Proinsulin multi-peptide immunotherapy induces antigen-specific regulatory T cells and limits autoimmunity in a humanized model.Clinical and experimental immunology · 2015
    Article
14. The role of lymphocytes in the development and treatment of alopecia areata.Expert review of clinical immunology · 2015
    Review
15. Can we vaccinate against Type 1 diabetes?F1000 biology reports · 2012
    Article
16. Protection against autoimmune diabetes by silkworm-produced GFP-tagged CTB-insulin fusion protein.Clinical & developmental immunology · 2011
    Article
17. Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition.Journal of immunology (Baltimore, Md. : 1950) · 2010
    Article
18. IFN-gamma and IL-10 islet-antigen-specific T cell responses in autoantibody-negative first-degree relatives of patients with type 1 diabetes.Diabetologia · 2010
    Article
19. Killer artificial antigen-presenting cells: the synthetic embodiment of a 'guided missile'.Immunotherapy · 2010
    Review
20. Neuroprotection in stroke by complement inhibition and immunoglobulin therapy.Neuroscience · 2009
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as