Evidence map›Paper›PMID 11899300›Full record

ReviewCurrent allergy and asthma reports2001

Susceptibility genes in asthma and allergy.

C Ober

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00005500 completednot on this map

Collaborative Studies on the Genetics of Asthma (CSGA)

TypeobservationalSponsorUniversity of MinnesotaRan1992 to 2002Enrolled50ConditionsAsthma, Lung Diseases
NCT00006512 completednot on this map

Characterizing a 5P-Linked BHR Susceptibility Locus

TypeobservationalSponsorUniversity of ChicagoRan2000 to 2005ConditionsAsthma, Lung Diseases
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

C OberDepartment of Human Genetics, University of Chicago, 940 E 58th Street, Chicago, IL 60637, USA. c-ober@genetics.uchicago.edu
University of Chicago · US

Funding

T CELL CO-STIMULATION IN ALLERGIC ASTHMAP50HL056399 · NHLBI · UNIVERSITY OF CHICAGO · PI WHITE, STEVEN R · 1996 to 2005
$9.1M
Positional Cloning of a 6p-linked Asthma GeneR01HL072414 · NHLBI · UNIVERSITY OF CHICAGO · PI OBER, CAROLE · 2003 to 2007
$3.0M
CHARACTERIZING A 5P-LINKED BHR SUSCEPTIBILITY LOCUSR01HL066533 · NHLBI · UNIVERSITY OF CHICAGO · PI OBER, CAROLE · 2000 to 2004
$2.4M
LINKAGE STUDIES OF ASTHMA--SEARCH FOR SUSCEPTIBILITY LOCU01HL049596 · NHLBI · UNIVERSITY OF CHICAGO · PI OBER, CAROLE · 1992 to 2001
$1.6M
NHLBI NIH HHS HL49596NHLBI NIH HHS HL56399NHLBI NIH HHS HL66533NHLBI NIH HHS P50 HL056399NHLBI NIH HHS R01 HL066533NHLBI NIH HHS R01 HL072414
6 · The paper itself

Abstract

Genome-wide screens for asthma and atopy susceptibility loci have been completed in six population samples. Despite the extensive clinical heterogeneity associated with these phenotypes, 20 chromosomal regions show evidence of linkage (P < 0.01) in three or more population samples. Thus, this survey suggests that at least 20 independent loci influence susceptibility to asthma, atopy, or associated phenotypes and indicates that the genetics of these phenotypes are truly complex. Ongoing studies are aimed at identifying the specific gene or genes in these regions that confer susceptibility to asthma or atopy.

Indexed as

Genetic Predisposition to DiseaseAsthmaFamily HealthHumansHypersensitivity, ImmediatePhenotype

Identifiers

PMID11899300
OpenAlexW1980186118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.