ArticleProceedings of the National Academy of Sciences of the United States of America2002
Intercellular trafficking of a KNOTTED1 green fluorescent protein fusion in the leaf and shoot meristem of Arabidopsis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- GHCU, a Molecular Chaperone, Regulates Leaf Curling by Modulating the Distribution of KNGH1 in Cotton.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Therapeutic value of homeoprotein signaling pathways.Frontiers in neuroscience · 2024Review
- The mRNA mobileome: challenges and opportunities for deciphering signals from the noise.The Plant cell · 2023Review
- Shuttling Homeoproteins and Their Biological Significance.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Developmental genetics of maize vegetative shoot architecture.Molecular breeding : new strategies in plant improvement · 2021Article
- Comparative Transcriptome Analysis inFrontiers in genetics · 2021Article
- Article
- Fluorescent reporters for functional analysis in rice leaves.Plant direct · 2020Article
- Coordination of meristem and boundary functions by transcription factors in the SHOOT MERISTEMLESS regulatory network.Development (Cambridge, England) · 2018Article
- A Salutary Role of Reactive Oxygen Species in Intercellular Tunnel-Mediated Communication.Frontiers in cell and developmental biology · 2018Review
- Phloem Proteomics Reveals New Lipid-Binding Proteins with a Putative Role in Lipid-Mediated Signaling.Frontiers in plant science · 2016Article
- Identification of evolutionarily conserved amino acid residues in homeodomain of KNOX proteins for intercellular trafficking.Plant signaling & behavior · 2014Article
- Callose homeostasis at plasmodesmata: molecular regulators and developmental relevance.Frontiers in plant science · 2014Article
- Article
- TALE and Shape: How to Make a Leaf Different.Plants (Basel, Switzerland) · 2013Review
- A plasmodesmal glycosyltransferase-like protein.PloS one · 2013Article
- Identification of lipids and lipid-binding proteins in phloem exudates from Arabidopsis thaliana.Journal of experimental botany · 2012Article
- The chaperonin CCT8 facilitates spread of tobamovirus infection.Plant signaling & behavior · 2012Article
- Plasmodesmata "in Communicado".Frontiers in plant science · 2012Article
- Analysis of Arabidopsis transcription factor families revealed extensive capacity for cell-to-cell movement as well as discrete trafficking patterns.Molecules and cells · 2011Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dominant mutations in the maize homeobox gene knotted1 (kn1) act nonautonomously during maize leaf development, indicating that Kn1 is involved in the generation or transmission of a developmental signal that passes from the inner layers of the leaf to epidermal cells. We previously found that this nonautonomous activity is correlated with the presence of KN1 protein in leaf epidermal cells, where KN1 mRNA could not be detected. Furthermore, KN1 protein expressed in Escherichia coli and labeled with a fluorescent dye can traffic between leaf mesophyll cells in microinjection assays. Here we show that green fluorescent protein (GFP)-tagged KN1 is able to traffic between epidermal cells of Arabidopsis and onion. When expressed in vivo, the GFP approximately KN1 fusion trafficked from internal tissues of the leaf to the epidermis, providing the first direct evidence, to our knowledge, that KN1 can traffic across different tissue layers in the leaf. Control GFP fusions did not show this intercellular trafficking ability. GFP approximately KN1 also trafficked in the shoot apical meristem, suggesting that cell-to-cell trafficking of KN1 may be involved in its normal function in meristem initiation and maintenance.
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