ReviewMolecular neurobiology2002
Neuregulin signaling via erbB receptor assemblies in the nervous system.
Review in Molecular neurobiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- The Roles of Long-Term Hyperhomocysteinemia and Micronutrient Supplementation in theFrontiers in aging neuroscience · 2022Article
- MiRNAs, lncRNAs, and circular RNAs as mediators in hypertension-related vascular smooth muscle cell dysfunction.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Review
- Angiotensin II inhibits apoptosis of mouse aortic smooth muscle cells through regulating the circNRG-1/miR-193b-5p/NRG-1 axis.Cell death & disease · 2019Article
- Effects of neuregulin-1 on autonomic nervous system remodeling post-myocardial infarction in a rat model.Neural regeneration research · 2017Article
- A peptide antagonist of ErbB receptors, Inherbin3, induces neurite outgrowth from rat cerebellar granule neurons through ErbB1 inhibition.Neurochemical research · 2013Article
- Signaling mechanisms regulating myelination in the central nervous system.Neuroscience bulletin · 2013Article
- A model selection approach to discover age-dependent gene expression patterns using quantile regression models.BMC genomics · 2009Article
- Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations.Molecular neurodegeneration · 2008Article
- Differential regulation of neuregulin 1 expression by progesterone in astrocytes and neurons.Neuron glia biology · 2006Article
- Neuregulin 1-Beta cytoprotective role in AML 12 mouse hepatocytes exposed to pentachlorophenol.International journal of environmental research and public health · 2006Article
- The ErbB4 neuregulin receptor mediates suppression of oligodendrocyte maturation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells.Functional & integrative genomics · 2005Article
- Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence.Molecular psychiatry · 2005Review
- Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia.Molecular psychiatry · 2004Article
- Back signaling by the Nrg-1 intracellular domain.The Journal of cell biology · 2003Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuregulins (NRG) play important roles in the development, maintenance, and repair of the nervous system, with influences on neuronal migration, synaptogenesis, receptor subunit composition, and the proliferation/survival of oligodendrocytes and Schwann cells. However, the precise detail of how the NRGs signal through ErbB receptors, particularly at central synapses, is incomplete. The receptor kinase domain provides sites for association with adaptor proteins. In addition, evidence from recent reports suggests that ErbB2/4 receptors, through their C-terminal amino acids, can form specific associations with scaffolding proteins. The existence of such assemblies expands the range of signaling cascades available to the NRGs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.