Evidence map›Paper›PMID 11889147›Full record

ArticleThe Journal of clinical endocrinology and metabolism2002

Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes.

Guillermo E Umpierrez, Scott D Isaacs, Niloofar Bazargan, Xiangdong You, Leonard M Thaler, Abbas E Kitabchi

8 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 656 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
656citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06187285 nacompletedstarted 2024, after this paper: background citation

Efficay and Safety of Empagliflozin Versus Sitagliptin for the In-patient Management of Hyperglycemia: Randomised Control

Ran2024Enrolled220Registered outcomes10Posted comparisons0ConditionsType 2 DiabetesArmsempagliflozin 25 mg, Sitagliptin 100mg
PMID 9527963PMID 27964837PMID 11588337PMID 11794168PMID 12105309PMID 19429873PMID 22223765PMID 37380728PMID 33915345other papers from this trial
Open the trial in the graph
NCT00984737 nacompletednot on this mapstarted 2007, after this paper: background citation

Newly Diagnosed Hyperglycemia and Stress Hyperglycemia in a Coronary Intensive Care Unit

TypeinterventionalSponsorBaskent UniversityRan2007 to 2008ConditionsDiabetes Mellitus, Hyperglycemia, Blood Glucose, Myocardial IschemiaArmsInsulin
NCT04542213 phase3completednot on this mapstarted 2020, after this paper: background citation

Effect of the Combination of Dipeptidyl Peptidase-4 Inhibitor (DPP4i) and Insulin in Comparison to Insulin on Metabolic Control and Prognosis in Hospitalized Patients With COVID-19

TypeinterventionalSponsorHospital Regional de Alta Especialidad del BajioRan2020 to 2021Enrolled70ConditionsHyperglycemia, Covid19ArmsLinagliptin tablet, Insulin
NCT04665128 unknown statusnot on this mapstarted 2020, after this paper: background citation

Determining the Factors That Affects Emergency Department Visits of Hyperglycemic Patients in 30 Days.

TypeobservationalSponsorDerince Training and Research HospitalRan2020 to 2021Enrolled120ConditionsHyperglycemia, Diabetes Mellitus, Emergencies
NCT04854135 naterminatednot on this mapstarted 2021, after this paper: background citation

Continuous Glucose Monitoring Initiation at Hospital Discharge: A Feasibility Pilot Study

TypeinterventionalSponsorWashington University School of MedicineRan2021 to 2022Enrolled20ConditionsType 1 Diabetes, Type2 Diabetes, Hyperglycemia, HypoglycemiaArmsCGM4Home
NCT05752929 phase4completednot on this mapstarted 2016, after this paper: background citation

Comparison of 2 Hyperglycemia-correction Scales in Hospitalized Patients in an Institution in Bogotá, Colombia

TypeinterventionalSponsorHospital Universitario Clinica San RafaelRan2016 to 2019Enrolled116ConditionsDiabete Type 2, HyperglycemiaArmsInsulin, insulin
NCT05803473 nacompletednot on this mapstarted 2023, after this paper: background citation

In-hospital Diabetes Management by a Diabetes Team and Continuous Glucose Monitoring or Point of Care Glucose Testing (DIATEC): a Randomised Trial

TypeinterventionalSponsorPeter KristensenRan2023 to 2024Enrolled166ConditionsDiabetes Mellitus, Type 2ArmsDexcom G6 Continuous Glucose Monitoring System (Dexcom Inc., San Diego, USA), FreeStyle Precision Pro Glucometer for glucose POC testing
NCT07769138 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the Intensive Care Unit (ICU-TeleCGM)

TypeobservationalSponsorImperial College Healthcare NHS TrustRan2026 to 2028Enrolled70ConditionsType 1 Diabetes, Type 2 Diabetes Treated With Insulin, Hyperglycemia, Intensive Care (ICU)ArmsDexcom G7, ViewsEMR telemetry
3 · Its place in the literature

Who cites it

656 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. [Hospital diabetes management (Update 2026)].Wiener klinische Wochenschrift · 2026
    Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  6. Guideline
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Trial
  12. Trial
  13. Randomized Study Comparing Continuous Glucose Monitoring and Capillary Glucose Testing in Patients With Type 2 Diabetes After Hospital Discharge.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Article
  20. Article

596 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Guillermo E UmpierrezDivision of Endocrinology and Metabolism, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA. gumpierrez@utmem.edu
Scott D Isaacs
Niloofar Bazargan
Xiangdong You
Leonard M Thaler
Abbas E Kitabchi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Admission hyperglycemia has been associated with increased hospital mortality in critically ill patients; however, it is not known whether hyperglycemia in patients admitted to general hospital wards is associated with poor outcome. The aim of this study was to determine the prevalence of in-hospital hyperglycemia and determine the survival and functional outcome of patients with hyperglycemia with and without a history of diabetes. We reviewed the medical records of 2030 consecutive adult patients admitted to Georgia Baptist Medical Center, a community teaching hospital in downtown Atlanta, GA, from July 1, 1998, to October 20, 1998. New hyperglycemia was defined as an admission or in-hospital fasting glucose level of 126 mg/dl (7 mmol/liter) or more or a random blood glucose level of 200 mg/dl (11.1 mmol/liter) or more on 2 or more determinations. Hyperglycemia was present in 38% of patients admitted to the hospital, of whom 26% had a known history of diabetes, and 12% had no history of diabetes before the admission. Newly discovered hyperglycemia was associated with higher in-hospital mortality rate (16%) compared with those patients with a prior history of diabetes (3%) and subjects with normoglycemia (1.7%; both P < 0.01). In addition, new hyperglycemic patients had a longer length of hospital stay, a higher admission rate to an intensive care unit, and were less likely to be discharged to home, frequently requiring transfer to a transitional care unit or nursing home facility. Our results indicate that in-hospital hyperglycemia is a common finding and represents an important marker of poor clinical outcome and mortality in patients with and without a history of diabetes. Patients with newly diagnosed hyperglycemia had a significantly higher mortality rate and a lower functional outcome than patients with a known history of diabetes or normoglycemia.

Indexed as

HospitalizationBlood GlucoseCritical CareDiabetes MellitusFastingFemaleHospitalsHumansHyperglycemiaLength of StayMaleMedical RecordsMiddle AgedPrognosisUnited StatesBlood Glucose

Identifiers

PMID11889147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.